Electric-drive and lightweight vehicles can reduce CO2 emissions in road passenger transportation. However, maximum reductions are limited by the extent of their diffusion. A vehicle fleet stock turnover model was developed to study the impact of powertrain electrification, vehicle size reduction and lightweight materials substitution on light-duty vehicle fleet energy consumption, CO2 emissions and cost; and used in the case of Japan. Vehicle types included internal combustion engine vehicles, hybrid electric vehicles, battery electric vehicles, and fuel cell hybrid electric vehicles; using two glider types, conventional and lightweight; available in three vehicle size classes, normal, compact and mini-sized vehicles. Diffusion of mini-sized lightweight battery electric vehicles has the largest potential for tank-to-wheel energy consumption and CO2 emissions reductions, 70.6 and 92.2%, compared to the 2050 baseline values; with a net cash flow larger than zero until 2045. In contrast, diffusion of mini-sized lightweight fuel cell hybrid electric vehicles has the lowest net cash flow by 2050, with negative values from 2033 and potential tank-to-wheel energy consumption and CO2 emissions reductions of 55.4 and 82.9% compared to the 2050 baseline values. Lightweighting reduces significantly the capital cost of battery electric vehicles and fuel cell hybrid electric vehicles, favoring their deployment. (C) 2015 Elsevier Ltd. All rights reserved.