The first series of chiral 2,2′:6′,2"-terpyridine tri-N-oxide ligands for Lewis base-catalyzed asymmetric allylation of aldehydes

被引：43

作者：

Wong, WL

Lee, CS

Leung, HK

Kwong, HL

机构：

[1] City Univ Hong Kong, Dept Biol & Chem, Kowloon, Hong Kong, Peoples R China

[2] City Univ Hong Kong, Open Lab Chirotechnol, Inst Mol Technol Drugs Discovery & Synth, Kowloon, Hong Kong, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2004年 / 2卷 / 14期

关键词：

D O I：

10.1039/b407933g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first series of chiral 2,2':6',2'-terpyridine tri-N-oxide ligands have been developed; They were showed to be active Lewis base-catalysts for asymmetric allylation of aldehydes using allyltrichlorosilane with optimal results at 0degreesC for electron-deficient aromatic aldehydes (yields up to 97% and enantioselectivities up to 86% ee).

引用

页码：1967 / 1969

页数：3

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