Prosthetic heart valve thrombosis during dicloxacillin therapy

被引：0
|
作者：
Halvorsen, S [1 ]
Husebye, T [1 ]
Arnesen, H [1 ]
机构：
[1] Ullevaal Univ Hosp, Dept Cardiol, NO-0407 Oslo, Norway
来源：
SCANDINAVIAN CARDIOVASCULAR JOURNAL | 1999年 / 33卷 / 06期
关键词：
dicloxacillin; mechanical aortic valve; thrombosis; warfarin;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 76-year-old woman receiving warfarin after aortic valve replacement experienced prosthetic valve thrombosis during dicloxacillin therapy. Successful thrombolysis was achieved with tissue plasminogen activator. The international normalized ratio (INR) on admission was reduced to 1.4 and an increased warfarin dosage was required for three weeks following discontinuation of dicloxacillin treatment in order to maintain therapeutic INRs. Careful monitoring of INRs and titration of the warfarin dosage is recommended when dicloxacillin is prescribed to patients receiving warfarin.
引用
收藏
页码：366 / 368
页数：3
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