How to build and rebuild a lens

被引：10
|
作者：
Tsonis, Panagiotis A. [1 ]
机构：
[1] Univ Dayton, Dept Biol, Dayton, OH 45469 USA
[2] Univ Dayton, Ctr Tissue Regenerat & Engn, Dayton, OH 45469 USA
来源：
JOURNAL OF ANATOMY | 2006年 / 209卷 / 04期
关键词：
engineering; evolution; eye; lens; regeneration; stem cells;
D O I：
10.1111/j.1469-7580.2006.00634.x
中图分类号：
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号：
100101 ;
摘要：
Evolution has used many different strategies to build eyes and lenses. However, the genetic regulation involved seems to be quite conserved. Likewise, the regeneration of eye structures is remarkable, especially in salamanders. This review outlines the basic mechanisms of lens regeneration and its induction and the possibility of creating lenses by transdifferentiation of the pigment epithelial cells, by stem cells or by bioengineering.
引用
收藏
页码：433 / 437
页数：5
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