Household Transmission of Influenza Virus

被引:82
|
作者
Tsang, Tim K. [1 ]
Lau, Lincoln L. H. [2 ]
Cauchemez, Simon [3 ]
Cowling, Benjamin J. [1 ]
机构
[1] Univ Hong Kong, Li Ka Shing Fac Med, Sch Publ Hlth, WHO Collaborating Ctr Infect Dis Epidemiol & Cont, Hong Kong, Hong Kong, Peoples R China
[2] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada
[3] Inst Pasteur, Math Modelling Infect Dis Unit, Paris, France
关键词
PANDEMIC H1N1 2009; ACUTE RESPIRATORY ILLNESS; SECONDARY ATTACK RATES; NEW-YORK-CITY; A H1N1; RISK-FACTORS; SEASONAL INFLUENZA; COMPARATIVE EPIDEMIOLOGY; OSELTAMIVIR TREATMENT; ANTIBODY-TITERS;
D O I
10.1016/j.tim.2015.10.012
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Human influenza viruses cause regular epidemics and occasional pandemics with a substantial public health burden. Household transmission studies have provided valuable information on the dynamics of influenza transmission. We reviewed published studies and found that once one household member is infected with influenza, the risk of infection in a household contact can be up to 38%, and the delay between onset in index and secondary cases is around 3 days. Younger age was associated with higher susceptibility. In the future, household transmission studies will provide information on transmission dynamics, including the correlation of virus shedding and symptoms with transmission, and the correlation of new measures of immunity with protection against infection.
引用
收藏
页码:123 / 133
页数:11
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