Ratiometric and Time-Resolved Fluorimetry from Quantum Dots Featuring Drug Carriers for Real-Time Monitoring of Drug Release in Situ

被引:45
|
作者
Gui, Rijun [1 ,2 ]
Wan, Ajun [2 ,3 ]
Zhang, Yalei [3 ]
Li, Huili [1 ]
Zhao, Tingting [2 ]
机构
[1] Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, Dept Chem, Shanghai 200240, Peoples R China
[3] Tongji Univ, Natl Engn Res Ctr Facil Agr, State Key Lab Pollut Control & Resources Reuse, Shanghai 200092, Peoples R China
基金
中国国家自然科学基金;
关键词
RESONANCE ENERGY-TRANSFER; MESOPOROUS SILICA NANOPARTICLES; FLUORESCENCE DETECTION; CARBON NANOTUBES; DELIVERY; PH; FRET; DOXORUBICIN; NANOSENSOR; BIOSENSORS;
D O I
10.1021/ac501293e
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
An effective ratiometric and time-resolved fluorimetry was described. On the basis of Forster resonance energy transfer (FRET) between semiconductor quantum dots (QDs) and fluorescent drugs, poly(ethylene glycol)-modified QDs were successfully prepared and further developed as QDs featuring carriers for real-time monitoring of drug release in situ.
引用
收藏
页码:5211 / 5214
页数:4
相关论文
共 50 条
  • [1] Real-time monitoring of drug release
    Weinstain, Roy
    Segal, Ehud
    Satchi-Fainaro, Ronit
    Shabat, Doron
    CHEMICAL COMMUNICATIONS, 2010, 46 (04) : 553 - 555
  • [2] Aptamer/graphene quantum dots capped fluorescent mesoporous silica for real-time monitoring of controlled drug release
    Zheng, Fenfen
    Zhu, Jun-Jie
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [3] Real-time electrochemical monitoring of drug release from therapeutic nanoparticles
    Mora, Laura
    Chumbimuni-Torres, Karin Y.
    Clawson, Corbin
    Hernandez, Lucas
    Zhang, Liangfang
    Wang, Joseph
    JOURNAL OF CONTROLLED RELEASE, 2009, 140 (01) : 69 - 73
  • [4] Aptamer/Graphene Quantum Dots Nanocomposite Capped Fluorescent Mesoporous Silica Nanoparticles for Intracellular Drug Delivery and Real-Time Monitoring of Drug Release
    Zheng, Fen-Fen
    Zhang, Peng-Hui
    Xi, Yu
    Chen, Jing-Jia
    Li, Ling-Ling
    Zhu, Jun-Jie
    ANALYTICAL CHEMISTRY, 2015, 87 (23) : 11739 - 11745
  • [5] Carbon nanomaterials as drug carriers: Real time drug release investigation
    Zhang, Renyun
    Olin, Hakan
    MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2012, 32 (05): : 1247 - 1252
  • [6] Monitoring drug levels in real-time
    Parks, Lisa
    BIOANALYSIS, 2014, 6 (08) : 1046 - 1046
  • [7] Cell chip device for real-time monitoring of drug release from drug-laden microparticles
    Choi, Hye Jin
    Shin, Min Chul
    Han, Ji Hwan
    Kim, Gyu Man
    LAB ON A CHIP, 2024, 24 (02) : 272 - 280
  • [8] AminoBODIPY Conjugates for Targeted Drug Delivery Systems and Real-Time Monitoring of Drug Release
    Porubsky, Martin
    Gurska, Sona
    Stankova, Jarmila
    Hajduch, Marian
    Dzubak, Petr
    Hlavac, Jan
    MOLECULAR PHARMACEUTICS, 2021, 18 (06) : 2385 - 2396
  • [9] Ultrafast release and capture of carriers in InGaAs/GaAs quantum dots observed by time-resolved terahertz spectroscopy
    Porte, H. P.
    Jepsen, P. Uhd
    Daghestani, N.
    Rafailov, E. U.
    Turchinovich, D.
    APPLIED PHYSICS LETTERS, 2009, 94 (26)
  • [10] Fluorescent Nanoparticles of Chitosan Complex for Real-Time Monitoring Drug Release
    Cui, Wei
    Lu, Xuemin
    Cui, Kun
    Wu, Jun
    Wei, Yen
    Let, Qinghua
    LANGMUIR, 2011, 27 (13) : 8384 - 8390