Multi-level collagen aggregates and their applications in biomedical applications

被引：17
|
作者：
Dan, Weihua [1 ,2 ]
Chen, Yining [1 ,2 ]
Dan, Nianhua [1 ,2 ]
Zheng, Xin [1 ,2 ]
Wang, Lu [1 ,2 ]
Yang, Changkai [1 ,2 ]
Huang, Yanping [1 ,2 ]
Liu, Xinhua [1 ,3 ]
Hu, Yang [1 ,4 ]
机构：
[1] Sichuan Univ, Minist Educ, Key Lab Leather Chem & Engn, Chengdu 610065, Sichuan, Peoples R China
[2] Sichuan Univ, Natl Engn Lab Clean Technol Leather Manufacture, Chengdu, Sichuan, Peoples R China
[3] Shaanxi Univ Sci & Technol, Coll Bioresources Chem & Mat Engn, Xian, Shaanxi, Peoples R China
[4] Huazhong Agr Univ, Key Lab Environm Correlat Dietol, Minist Educ, Wuhan, Hubei, Peoples R China
来源：
INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION | 2019年 / 24卷 / 08期
基金：
中国国家自然科学基金;
关键词：
Collagen; collagen fibers; collagen aggregates; collagen modification and application; ACELLULAR DERMAL MATRIX; OXIDIZED CHITOSAN OLIGOSACCHARIDE; CROSS-LINKING; BREAST RECONSTRUCTION; ELECTROSPUN; DIALDEHYDE; BONE; FEASIBILITY; FILM;
D O I：
10.1080/1023666X.2019.1656387
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
In this review, the system of multi-level collagen aggregates including collagen molecular, collagen fiber, advanced collagen aggregates, and tissues was reviewed. The preparation methods of multi-level collagen aggregates were introduced, and the relationship between structure and properties of them was analyzed and clarified. The general rule of structure-activity relationship of multi-level collagen aggregates under different modifiers and modified conditions was analyzed, and a theoretical basis for the application of multi-level collagen aggregates in biomedical field was provided. Finally, the applications of a series of biomedical materials of multi-level collagen aggregates and their modified products were listed. It is confirmed that the application field of multi-level collagen aggregates and their modified products might be far greater than collagen and other biomass. The multi-level collagen aggregates might have a very broad application prospect.
引用
收藏
页码：667 / 683
页数：17
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