Efforts towards elucidating the chemical mechanism and role of the GlcNAc 2-epimerase in the cell

被引：0
|
作者：
Luchansky, SJ
Yarema, KJ
Bertozzi, CR
机构：
[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
[2] Johns Hopkins Univ, Whitaker Biomed Engn Inst, Baltimore, MD 21218 USA
[3] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
[4] Univ Calif Berkeley, Howard Hughes Med Inst, Berkeley, CA 94720 USA
[5] Univ Calif Berkeley, Lawrence Berkeley Lab, Ctr Adv Mat, Berkeley, CA 94720 USA
来源：
GLYCOBIOLOGY | 2002年 / 12卷 / 10期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
145
引用
收藏
页码：690 / 690
页数：1
相关论文
共 50 条
  • [1] Possible role of UDP-GlcNAc 2-epimerase /ManNAc kinase (GNE) in cell
    Singh, R.
    Arya, R.
    MOLECULAR BIOLOGY OF THE CELL, 2014, 25
  • [2] UDP-GlcNAc 2-epimerase: A regulator of cell surface sialylation
    Keppler, OT
    Hinderlich, S
    Langner, J
    Schwartz-Albiez, R
    Reutter, W
    Pawlita, M
    GLYCOBIOLOGY, 1999, 9 (10) : 1132 - 1133
  • [3] UDP-GlcNAc 2-epimerase: A regulator of cell surface sialylation
    Keppler, OT
    Hinderlich, S
    Langner, J
    Schwartz-Albiez, R
    Reutter, W
    Pawlita, M
    SCIENCE, 1999, 284 (5418) : 1372 - 1376
  • [4] GlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolism
    Luchansky, SJ
    Yarema, KJ
    Takahashi, S
    Bertozzi, CR
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (10) : 8035 - 8042
  • [5] Unnatural substrate specificity and preliminary mechanistic details of the GlcNAc 2-epimerase
    Luchansky, SJ
    Bertozzi, CR
    GLYCOBIOLOGY, 2001, 11 (10) : 910 - 910
  • [6] Small Molecules Targeting Human UDP-GlcNAc 2-Epimerase
    Lopez, Jacob L. Gorenflos
    Dornan, Gillian L.
    Boback, Nico
    Neuenschwander, Martin
    Oder, Andreas
    Kemnitz-Hassanin, Kristin
    Schmieder, Peter
    Specker, Edgar
    Asikoglu, Hatice Ceyda
    Oberdanner, Christian
    Seyffarth, Carola
    von Kries, Jens Peter
    Lauster, Daniel
    Hinderlich, Stephan
    Hackenberger, Christian P. R.
    CHEMBIOCHEM, 2023, 24 (24)
  • [7] Mechanism and inhibition of human UDP-GlcNAc 2-epimerase, the key enzyme in sialic acid biosynthesis
    Sheng-Chia Chen
    Chi-Hung Huang
    Shu-Jung Lai
    Chia Shin Yang
    Tzu-Hung Hsiao
    Ching-Heng Lin
    Pin-Kuei Fu
    Tzu-Ping Ko
    Yeh Chen
    Scientific Reports, 6
  • [8] Mechanism and inhibition of human UDP-GlcNAc 2-epimerase, the key enzyme in sialic acid biosynthesis
    Chen, Sheng-Chia
    Huang, Chi-Hung
    Lai, Shu-Jung
    Yang, Chia Shin
    Hsiao, Tzu-Hung
    Lin, Ching-Heng
    Fu, Pin-Kuei
    Ko, Tzu-Ping
    Chen, Yeh
    SCIENTIFIC REPORTS, 2016, 6
  • [9] C-glycosidic UDP-GlcNAc analogues as inhibitors of UDP-GlcNAc 2-epimerase
    Stolz, F
    Blume, A
    Hinderlich, S
    Reutter, W
    Schmidt, RR
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2004, 2004 (15) : 3304 - 3312
  • [10] UDP-GlcNAc 2-epimerase activity in hereditary inclusion body myopathy
    Sparks, S
    Lalor, M
    Orvisky, E
    Huizing, M
    Krasnewich, D
    Sun, MS
    Dalakas, M
    Gahl, W
    AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 73 (05) : 448 - 448
12345