Cargo takes control of endocytosis

被引：19

作者：

Haucke, Volker ^{[1
]}

机构：

[1] Free Univ Berlin, Biochim Membranes Lab, Inst Chem & Biochem, D-14195 Berlin, Germany

来源：

CELL | 2006年 / 127卷 / 01期

关键词：

D O I：

10.1016/j.cell.2006.09.012

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Clathrin-mediated endocytosis is a major route for diverse cargo to enter the cellular endocytic pathway. New findings by Puthenveedu and von Zastrow (2006) suggest that certain cargo proteins, such as G protein coupled receptors that bind to PDZ domains, regulate their own targeting to a subset of clathrin-coated pits. Thus, cargo proteins may cause functional specialization of vesicle trafficking within the early endocytic pathway.

引用

页码：35 / 37

页数：3

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