Design and Synthesis of Biodegradable Grafted Cationic Polycarbonates as Broad Spectrum Antimicrobial Agents

被引:17
|
作者
Ong, Zhan Yuin [1 ]
Coady, Daniel J. [2 ]
Tan, Jeremy P. K. [1 ]
Li, Yan [1 ]
Chan, Julian M. W. [2 ]
Yang, Yi Yan [1 ]
Hedrick, James L. [2 ]
机构
[1] Inst Bioengn & Nanotechnol, 31 Biopolis Way, Singapore 138669, Singapore
[2] IBM Corp, Almaden Res Ctr, 650 Harry Rd, San Jose, CA 95120 USA
关键词
biocompatibility; biodegradability; biological applications of polymers; biomaterials; graft copolymers; polycarbonates; ring-opening polymerization; water-soluble polymers; CYCLIC CARBONATE; GENE DELIVERY; DENDRIMERS; NANOSTRUCTURES; POLYMERS; SURFACES; AMINE;
D O I
10.1002/pola.27987
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Several biodegradable grafted cationic polycarbonates prepared via metal-free organocatalytic ring-opening polymerization are investigated for their antimicrobial activity, mechanism of action, and biocompatibility. © 2015 Wiley Periodicals, Inc.
引用
收藏
页码:1029 / 1035
页数:7
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