Selectivity in oxidation catalysis

Selectivity in oxidation catalysis has been reviewed for conventional catalysts used for the production of bulk chemicals and epoxidations. The point of activation of the substrate is identified as a key factor identifying three mechanistic features. These are (i) activation of the weakest C-H bond in a substrate, (ii) activation of the strongest C-H bond and (iii) electrophilic attack in olefins. Key features of each type of reaction are identified and new catalyst types needed to break through existing selectivity barriers are discussed.