Synthesis of 1,3-Diynes Using Calcium Carbide as an Alkyne Source

被引：30
|
作者：
Liu, Zhenrong [1 ]
Li, Zheng [1 ]
机构：
[1] Northwest Normal Univ, Coll Chem & Chem Engn, Lanzhou 730070, Gansu, Peoples R China
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2021年 / 2021卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Alkynes; Calcium carbide; 1; 3-Diynes; Homogeneous catalysis; Synthetic methods; COPE-TYPE HYDROAMINATION; ONE-POT SYNTHESIS; METAL-FREE; TERMINAL ALKYNES; STEREOSELECTIVE-SYNTHESIS; COUPLING REACTIONS; ACETYLENE SOURCE; COPPER; EFFICIENT; FLUORIDE;
D O I：
10.1002/ejoc.202001324
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple method for the synthesis of 1,3-diynes from iodoarenes using calcium carbide as an alkyne source and air as an oxidant is described. A series of 1,4-diarylbuta-1,3-diynes were efficiently synthesized by this strategy. The salient features of this protocol are the use of inexpensive and easy-to-handle alkyne source, broad substrate scope, open-air condition, and simple operation procedure.
引用
收藏
页码：302 / 308
页数：7
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