Caregiver strain among life partners of persons with mild disability due to relapsing-remitting multiple sclerosis

被引：12

作者：

van der Hiele, K. ^{[1
,2
,3
,4
]}

van Gorp, D. A. M. ^{[1
,2
,3
,4
,5
]}

Heerings, M. A. P. ^{[3
]}

Jongen, P. J. ^{[6
,7
]}

van der Klink, J. J. L. ^{[8
]}

Beenakker, E. A. C. ^{[9
]}

van Eijk, J. J. J. ^{[10
]}

Frequin, S. T. F. M. ^{[11
]}

van Geel, B. M. ^{[12
]}

Hengstrnan, G. J. D. ^{[13
]}

Hoitsma, E. ^{[14
]}

Mostere, J. P. ^{[15
]}

Verhagen, W. I. M. ^{[16
]}

de Gans, K. ^{[17
]}

Zemel, D. ^{[18
]}

Middelkoop, H. A. M. ^{[1
,2
,19
]}

Visser, L. H. ^{[4
,5
]}

机构：

[1] Leiden Univ, Inst Psychol Hlth Med, POB 9555, NL-2300 RB Leiden, Netherlands

[2] Leiden Univ, Neuropsychol Unit, POB 9555, NL-2300 RB Leiden, Netherlands

[3] Natl Multiple Sclerosis Fdn, Mathenesserlaan 378, NL-3023 HB Rotterdam, Netherlands

[4] Elisabeth TweeSteden Hosp, Dept Neurol, POB 90151, NL-5000 LC Tilburg, Netherlands

[5] Univ Humanist Studies, Dept Care Eth, POB 797, NL-3500 AT Utrecht, Netherlands

[6] MS4 Res Inst, Ubbergseweg 34, NL-9522 KJ Nijmegen, Netherlands

[7] Univ Groningen, Univ Med Ctr Groningen, Dept Community & Occupat Med, POB 30001, NL-9700 RB Groningen, Netherlands

[8] Tilburg Univ, Tilburg Sch Social & Behav Sci, Tranzo Sci Ctr Care & Welf, POB 90153, NL-5000 LE Tilburg, Netherlands

[9] Med Ctr Leeuwarden, Dept Neurol, POB 888, NL-8901 BR Leeuwarden, Netherlands

[10] Jeroen Bosch Hosp, Dept Neurol, POB 90153, NL-2000 ME sHertogenbosch, Netherlands

[11] St Antonius Hosp, Dept Neurol, POB 2500, NL-3430 EM Nieuwegein, Netherlands

[12] Northwest Clin Alkmaar, Dept Neurol, Postbus 501, NL-1800 AM Alkmaar, Netherlands

[13] Catharina Hosp, Dept Neurol, POB 1350, NL-5602 ZA Eindhoven, Netherlands

[14] Alrijne Hosp Leiden, Dept Neurol, POB 9650, NL-2300 RD Leiden, Netherlands

[15] Rijnstate Hosp, Dept Neurol, POB 9555, NL-6800 TA Arnhem, Netherlands

[16] Canisius Wilhelmina Hosp, Dept Neurol, POB 9015, NL-6500 GS Nijmegen, Netherlands

[17] Groene Hart Hosp, Dept Neurol, POB 1098, NL-2800 BB Gouda, Netherlands

[18] Albert Schweitzer Hosp, Dept Neurol, POB 444, NL-3300 AK Dordrecht, Netherlands

[19] Leiden Univ, Med Ctr, Dept Neurol, POB 9600, NL-2300 RC Leiden, Netherlands

来源：

MULTIPLE SCLEROSIS AND RELATED DISORDERS | 2019年 / 31卷

关键词：

Multiple sclerosis; Life partners; Caregiver strain; Neuropsychiatry; Cognition; BURDEN; RELIABILITY; DEPRESSION; VALIDITY; PEOPLE; INVENTORY; QUALITY; ANXIETY; CARERS; IMPACT;

D O I：

10.1016/j.msard.2019.03.005

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: Multiple sclerosis (MS) is a chronic disorder of the central nervous system with an unpredictable disease course. Life partners often become caregivers, which can be both rewarding and challenging, as the caregiver's physical and mental health is often negatively affected. Previous studies on caregiver strain focused on caregivers of persons with MS with relatively high disability levels, while caregiver strain may already be experienced by life partners living with mildly disabled persons with MS. Objective: The current study examines factors associated with caregiver strain in life partners of persons with mild disability due to relapsing-remitting MS. Methods: We included 173 persons with relapsing-remitting MS (79% female; mean age 42.8 years; 90% employed; median EDSS 2.0) and their life partners. The life partners completed questionnaires on caregiver strain and neuropsychiatric and cognitive functioning of the person with MS. The persons with MS completed questionnaires about demographics, fatigue, personality, physical, cognitive and neuropsychiatric functioning, and underwent neuropsychological and neurological examinations. A linear regression analysis was conducted to examine predictors of caregiver strain. Results: 24% of the life partners experienced above average levels of caregiver strain. A multivariate linear regression analysis revealed that a higher age of the person with MS (beta = 0.16, p = 0.04), more physical disability (beta = 0.17p = 0.04), more cognitive and neuropsychiatric problems of the person with MS as reported by the life partner (beta = 0.33, p = 0.001) and higher severity of neuropsychiatric symptoms as reported by the life partner (beta = 0.32, p = 0.001) were associated with higher caregiver strain (R-2 = 0.49). Conclusion: Higher caregiver strain in life partners of persons with mild disability due to relapsing-remitting MS was primarily associated with cognitive and neuropsychiatric problems of the person with MS.

引用

页码：5 / 11

页数：7

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