This paper has constructed a credit evaluation index system for SMEs basing on 6 factors: profitability, solvency, growth ability, operating efficiency, technological innovative ability and enterprise quality, as well as 28 financial and non-financial indexes in detail. To solve the contradiction of subjective weighting method and objective weighting method, and uncertainty of quantitative description for drought risk assessment index and the judge of assessment result, combination weighting method and fuzzy integrated evaluation have been introduced to construct the assessment model of high-tech SMEs. At last, we launch the empirical analysis on 30 listed SMEs from Shenzhen SME board, and the result demonstrates the feasibility of the model.