Retransplantation using living-donor right-liver grafts

被引:10
|
作者
Dai, Wing Chiu [1 ]
Chan, See Ching [1 ]
Chok, Kenneth S. H. [1 ]
Cheung, Tan To [1 ]
Sharr, William W. [1 ]
Chan, Albert C. Y. [1 ]
Fung, James Y. Y. [2 ]
Wong, Tiffany C. L. [1 ]
Lo, Chung Mau [1 ]
机构
[1] Univ Hong Kong, Queen Mary Hosp, Dept Surg, Hong Kong, Hong Kong, Peoples R China
[2] Univ Hong Kong, Queen Mary Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China
关键词
Living donor; Retransplantation; Right liver graft; SINGLE-CENTER EXPERIENCE; HEPATITIS-C INFECTION; LONG-TERM SURVIVAL; RISK-FACTORS; TRANSPLANT RECIPIENTS; CONSECUTIVE PATIENTS; FOLLOW-UP; OUTCOMES; FAILURE; MORTALITY;
D O I
10.1002/jhbp.100
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background This study reviews the outcomes of retransplantation using living-donor right-liver grafts. Methods A retrospective study of liver retransplants performed between 1996 and 2013 was conducted. The retransplants were divided into the DD group (with deceased donors) and the LD group (with living donors). Survival outcomes were analyzed. Results The DD group contained 23 patients and 27 retransplants using whole-liver grafts and the LD group contained 11 patients and 11 retransplants using right-liver grafts. Vascular and biliary complications were the main indications for retransplantation in both groups. The LD group had significantly younger donors, lighter grafts, shorter cold ischemia and longer operations. The two groups were comparable in age, preoperative liver function, warm ischemia, blood loss, transfusion, intensive care unit stay, hospital stay, hospital mortality, complication and graft loss. The 1-year, 3-year and 5-year patient survival rates were 78.3%, 73.7% and 63.8%, respectively, in the DD group. The LD group had the corresponding rates all at 90.9% (P = 0.246). The 1-year, 3-year and 5-year graft survival rates were 74.1%, 65.8% and 61.5%, respectively, in the DD group. The LD group had the corresponding rates all at 90.9% (P = 0.132). Conclusion Excellent long-term survival after retransplantation using living-donor right-liver grafts can be achieved.
引用
收藏
页码:579 / 584
页数:6
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