Zoledronic acid in chronic rotator cuff tears Improvement of the functional outcome in a rat model

被引：0
|
作者：
Schanda, Jakob E. [1 ,2 ]
Mittermayr, Rainer [1 ,2 ]
Redl, Heinz [2 ]
Fialka, Christian [1 ]
Muschitz, Christian [3 ]
机构：
[1] Standort Meidling, AUVA Traumazentrum Wien, Abt Traumatol, Vienna, Austria
[2] Ludwig Boltzmann Inst Expt & Klin Traumatol, Vienna, Austria
[3] Krankenhaus Barmherzigen Schwestern Wien, Med Abt 2, Vienna, Austria
来源：
ARTHROSKOPIE | 2021年 / 34卷 / 01期
关键词：
Shoulder; Reconstruction; mu-computed tomography; Biomechanical testing; Histology; BONE-MINERAL DENSITY;
D O I：
10.1007/s00142-020-00431-w
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The effect of zoledronic acid was investigated in a rat model to counteract the bone loss at the humeral head of chronic rotator cuff lesions. A total of 32 male Sprague-Dawley rats underwent a unilateral tenotomy of the supraspinatus tendon. Three weeks later, all animals underwent transosseous rotator cuff reconstruction. Zoledronic acid provides an increase of bone microarchitecture at the humeral head as well as improved biomechanical properties of the enthesis compared to an untreated control group.
引用
收藏
页码：59 / 61
页数：3
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