Revisit gut microbiota and its impact on human health and disease

被引:150
|
作者
Ding, Rui-xue [1 ]
Goh, Wei-Rui [2 ]
Wu, Ri-na [1 ]
Yue, Xi-qing [1 ]
Luo, Xue [1 ]
Khine, Wei Wei Thwe [2 ]
Wu, Jun-rui [1 ]
Lee, Yuan-Kun [2 ]
机构
[1] Shenyang Agr Univ, Coll Food Sci, Shenyang 110866, Liaoning, Peoples R China
[2] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Microbiol & Immunol, 5 Sci Dr 2, Singapore 117597, Singapore
关键词
Gut microbiota; Human health; Disease; ABERRANT INTESTINAL MICROBIOTA; SERUM METABOLOME; CANCER; ASSOCIATION; PREVENTION; METFORMIN; OBESITY; ATHEROSCLEROSIS; HYPERTENSION; TRANSLATION;
D O I
10.1016/j.jfda.2018.12.012
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Trillions of microbes have evolved with and continue to live on human beings. With the rapid advances in tools and technology in recent years, new knowledge and insight in cross-talk between the microbes and their hosts have gained. It is the aim of this work to critically review and summarize recent literature reports on the role of microbiota and mechanisms involved in the progress and development of major human diseases, which include obesity, hypertension, cardiovascular disease, diabetes, cancer, Inflammatory Bowel Disease (IBD), gout, depression and arthritis, as well as infant health and longevity. Copyright (C) 2019, Food and Drug Administration, Taiwan. Published by Elsevier Taiwan LLC.
引用
收藏
页码:623 / 631
页数:9
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