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Primary open-angle glaucoma
被引:1592
|作者:
Weinreb, RN
Khaw, PT
机构:
[1] Univ Calif San Diego, Hamilton Glaucoma Ctr, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Dept Ophthalmol, La Jolla, CA 92093 USA
[3] Moorfields Eye Hosp, Glaucoma Unit, London, England
[4] Moorfields Eye Hosp, Ocular Repair & Regenerat Biol Unit, London, England
[5] UCL, Inst Ophthalmol, London, England
来源:
关键词:
D O I:
10.1016/S0140-6736(04)16257-0
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Primary open-angle glaucoma is a progressive optic neuropathy and, perhaps, the most common form of glaucoma. Because the disease is treatable, and because the visual impairment caused by glaucoma is irreversible, early detection is essential. Early diagnosis depends on examination of the optic disc, retinal nerve fibre layer, and visual field. New imaging and psychophysical tests can improve both detection and monitoring of the progression of the disease. Recently completed long-term clinical trials provide convincing evidence that lowering intraocular pressure prevents progression at both the early and late stages of the disease. The degree of protection is related to the degree to which intraocular pressure is lowered. Improvements in therapy consist of more effective and better-tolerated drugs to lower intraocular pressure, and more effective surgical procedures. New treatments to directly treat and protect the retinal ganglion cells that are damaged in glaucoma are also in development.
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页码:1711 / 1720
页数:10
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