Microarray image processing and quality control

被引:16
|
作者
Petrov, A [1 ]
Shams, S [1 ]
机构
[1] BioDiscovery Inc, El Segundo, CA 90245 USA
关键词
microarray image processing; image segmentation; microarray quality control; microarray batch automation; cDNA microarrays;
D O I
10.1023/B:VLSI.0000042488.08307.ad
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Image processing is an important stage of every microarray experiment. Reliability of this stage strongly influences the results of data analysis performed on extracted gene expressions. Multiple methods related to array recognition, spot segmentation and measurement extraction have emerged in this area over past several years. Currently there are various commercial and freeware packages available, which perform microarray image analysis. This paper attempts to review microarray image analysis as a whole and to make some experimental comparison of several computational schemes for signal segmentation and measurement extraction. Also we provide a detailed discussion of automated image quality control for use with microarray images.
引用
收藏
页码:211 / 226
页数:16
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