History and diagnostic value of antibodies to citrullinated proteins in rheumatoid arthritis

被引：17
|
作者：
Peene, I [1 ]
De Rycke, L [1 ]
Baeten, D [1 ]
Hoffman, I [1 ]
Veys, EM [1 ]
De Keyser, F [1 ]
机构：
[1] Ghent Univ Hosp, Dept Rheumatol, B-9000 Ghent, Belgium
来源：
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2004年 / 17卷 / 02期
关键词：
anti-citrillunated protein antibodies; rheumatoid arthritis;
D O I：
10.1177/039463200401700202
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Rheumatoid arthritis is a chronic inflammatory joint disease characterized by the presence of autoantibodies. The best known autoantibody is the rheumatoid factor. Another group of antibodies directed against citrullinated epitopes is proven to be more specific for rheumatoid arthritis. This review gives an overview of the history of the different anti-citrullinated protein antibody detection methods and their diagnostic and prognostic properties in RA.
引用
收藏
页码：107 / 115
页数：9
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