One-pot synthesis of 2-alkyl-4(5)-aryl-1H-imidazoles from 1-aryl-2-bromoethanones, ammonium carbonate and aliphatic carboxylic acids

被引：3
|
作者：
Liu, Cong [1 ]
Nie, Yijiao [1 ]
Yao, Guowei [1 ]
Dai, Rongji [1 ]
Deng, Yulin [1 ]
机构：
[1] Beijing Inst Technol, Sch Life Sci, Beijing 100081, Peoples R China
来源：
JOURNAL OF CHEMICAL RESEARCH | 2014年 / 04期
关键词：
heterocycles; imidazoles; aryl methyl ketones; aliphatic acids; ammonium carbonate; IMIDAZOLES; DERIVATIVES;
D O I：
10.3184/174751914X13932684206700
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A simple and efficient protocol for the preparation of 2-alkyl-4(5)-aryl-1H- imidazoles starting from a-bromo aryl methyl ketones and aliphatic carboxylic acids in the presence of ammonium carbonate has been developed.
引用
收藏
页码：208 / 210
页数：3
相关论文
共 50 条
  • [1] SYNTHESIS OF 2-AROYL-1-METHYL-1H-IMIDAZOLES USING ARYL CARBOXYLIC ACIDS
    Oyama, Kin-ichi
    Watanabe, Noriyuki
    Yoshida, Kumi
    [J]. HETEROCYCLES, 2017, 95 (02) : 1177 - 1183
  • [2] Polyfunctional imidazoles: VI. Synthesis of 2-amino-1-aryl-4-chloro-1H-imidazole-5-carboxylic acids derivatives
    Chornous, V. A.
    Grozav, A. N.
    Vovk, M. V.
    [J]. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2012, 48 (05) : 705 - 712
  • [3] Polyfunctional imidazoles: VI. Synthesis of 2-amino-1-aryl-4-chloro-1H-imidazole-5-carboxylic acids derivatives
    V. A. Chornous
    A. N. Grozav
    M. V. Vovk
    [J]. Russian Journal of Organic Chemistry, 2012, 48 : 705 - 712
  • [4] One-pot synthesis of alkyl 3-aryl-2-(4-phenyl-1H-1,2,3-triazol-1-yl)propanoates
    N. T. Pokhodylo
    R. D. Savka
    M. D. Obushak
    [J]. Russian Journal of Organic Chemistry, 2017, 53 : 734 - 737
  • [5] One-pot synthesis of alkyl 3-aryl-2-(4-phenyl-1H-1,2,3-triazol-1-yl)propanoates
    Pokhodylo, N. T.
    Savka, R. D.
    Obushak, M. D.
    [J]. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2017, 53 (05) : 734 - 737
  • [6] One-pot efficient synthesis of 2-Aryl-1-arylmethyl-1H-benzimidazoles and 2,4,5-Triaryl-1H-imidazoles using oxalic acid catalyst
    Kokare, Nagnnath D.
    Sangshetti, Jaiprakash N.
    Shinde, Devanand B.
    [J]. SYNTHESIS-STUTTGART, 2007, (18): : 2829 - 2834
  • [7] A NOVEL ONE-POT SYNTHESIS OF 2-ARYL-2H-1-BENZOPYRAN-3(4H)-ONES
    RAO, TS
    TRIVEDI, GK
    [J]. INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1985, 24 (11): : 1159 - 1160
  • [8] Efficient and practical synthesis of 4(5)-Aryl-1H-imidazoles and 2,4(5)-Diaryl-1H-imidazoles via highly selective palladium-catalyzed arylation reactions
    Bellina, Fabio
    Cauteruccio, Silvia
    Rossi, Renzo
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2007, 72 (22): : 8543 - 8546
  • [9] Novel one-pot synthesis of (4 or 5)-aryl-2-aryloyl-(1H)-imidazoles in water and tauto-isomerization study using NMR
    Khalili, Behzad
    Tondro, Tahereh
    Hashemi, Mohammed M.
    [J]. TETRAHEDRON, 2009, 65 (34) : 6882 - 6887
  • [10] New approach to the multicomponent one-pot synthesis of 2-aryl-1H-phenanthro[9,10-d]imidazoles
    Damavandi, Saman
    [J]. HETEROCYCLIC COMMUNICATIONS, 2011, 17 (1-2) : 79 - 81
12345