CYP2D6-HUMANIZED MICE AS A MODEL TO STUDY ALTERED DRUG METABOLISM DURING PREGNANCY

被引：0
|
作者：
Jeong, Hyun-Young [1 ]
机构：
[1] Univ Illinois, Chicago, IL USA
来源：
DRUG METABOLISM AND PHARMACOKINETICS | 2017年 / 32卷 / 01期
关键词：
D O I：
10.1016/j.dmpk.2016.10.035
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
S14
引用
收藏
页码：S7 / S7
页数：1
相关论文
共 50 条
  • [1] Altered expression of small heterodimer partner governs CYP2D6 induction during pregnancy in CYP2D6-humanized mice
    Jeong, Hyunyoung
    Pan, Xian
    Koh, Kwihye
    Yu, Ai-Ming
    Isoherranen, Nina
    [J]. FASEB JOURNAL, 2014, 28 (01):
  • [2] Induction of CYP2D6 Expression in CYP2D6-Humanized Transgenic Mouse during Pregnancy
    Jeong, Hyunyoung
    Koh, Kwi Hye
    Yu, Ai-Ming
    [J]. JOURNAL OF WOMENS HEALTH, 2010, 19 (10) : 1786 - 1786
  • [3] Altered Expression of Small Heterodimer Partner Governs Cytochrome P450 (CYP) 2D6 Induction during Pregnancy in CYP2D6-humanized Mice
    Koh, Kwi Hye
    Pan, Xian
    Shen, Hong-Wu
    Arnold, Samuel L. M.
    Yu, Ai-Ming
    Gonzalez, Frank J.
    Isoherranen, Nina
    Jeong, Hyunyoung
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (06) : 3105 - 3113
  • [4] Cholic acid feeding increases CYP2D6 expression in CYP2D6-humanized mice
    Kent, Rebecca
    Pan, Xian
    Jeong, Hyunyoung
    [J]. FASEB JOURNAL, 2016, 30
  • [5] Cholic Acid Feeding Leads to Increased CYP2D6 Expression in CYP2D6-Humanized Mice
    Pan, Xian
    Kent, Rebecca
    Won, Kyoung-Jae
    Jeong, Hyunyoung
    [J]. DRUG METABOLISM AND DISPOSITION, 2017, 45 (04) : 346 - 352
  • [6] Desipramine metabolism is comparable in CYP2D6-humanized mouse and human liver microsomes
    Shen, Hongwu
    Yu, Ai-Ming
    [J]. DRUG METABOLISM REVIEWS, 2009, 41 : 137 - 137
  • [7] Estrogen-Induced Cholestasis Leads to Repressed CYP2D6 Expression in CYP2D6-Humanized Mice
    Pan, Xian
    Jeong, Hyunyoung
    [J]. MOLECULAR PHARMACOLOGY, 2015, 88 (01) : 106 - 112
  • [8] Application of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug-Drug Interaction with Antidepressants
    MacLeod, A. Kenneth
    McLaughlin, Lesley A.
    Henderson, Colin J.
    Wolf, C. Roland
    [J]. DRUG METABOLISM AND DISPOSITION, 2017, 45 (01) : 17 - 22
  • [9] Kruppel-Like Factor 9 Promotes Hepatic Cytochrome P450 2D6 Expression during Pregnancy in CYP2D6-Humanized Mice
    Koh, Kwi Hye
    Pan, Xian
    Zhang, Wei
    McLachlan, Alan
    Urrutia, Raul
    Jeong, Hyunyoung
    [J]. MOLECULAR PHARMACOLOGY, 2014, 86 (06) : 727 - 735
  • [10] Sex steroid hormones differentially regulate CYP2D in female wild-type and CYP2D6-humanized mice
    Konstandi, Maria
    Andriopoulou, Christina E.
    Cheng, Jie
    Gonzalez, Frank J.
    [J]. JOURNAL OF ENDOCRINOLOGY, 2020, 245 (02) : 301 - 314
12345