Structural Reorganization of the Adrenal Cortex in OXYS Rats during Ontogeny

被引:0
|
作者
Lushnikova, E. L. [1 ]
Koldysheva, E. V. [1 ]
Molodykh, O. P. [1 ]
机构
[1] Russian Acad Med Sci, Dept Cellular Biol & Morphol, Inst Reg Pathol & Pathomorphol, Siberian Div, Novosibirsk, Russia
关键词
OXYS rats; gerontogeny; adrenal cortex; morphometry; stereology;
D O I
10.1007/s10517-009-0437-y
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Study of the structural reorganization of the adrenal cortex in OXYS and Wistar rats during aging showed that age-associated reorganization of the adrenal cortex in these rats consisted in atrophy, particularly pronounced in OXYS rats. Age-specific changes in the architectonics of the organ were noted mainly in the zona glomeruloza and zona fasciculata. The vessel-parenchyma relationships play the key role in the spatial reorganization of the adrenal cortex in OXYS and Wistar rats. The volume density of the sinusoidal capillaries in the zona fasciculata and zona reticularis increases during the late ontogeny, particularly so in Wistar rats, causing, in turn, an increase of the stroma/parenchyma volume proportion.
引用
收藏
页码:94 / 99
页数:6
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