An intelligent detection method for high-field asymmetric waveform ion mobility spectrometry

被引：3

作者：

Li, Yue ^{[1
]}

Yu, Jianwen ^{[1
]}

Ruan, Zhiming ^{[2
]}

Chen, Chilai ^{[2
]}

Chen, Ran ^{[3
]}

Wang, Han ^{[2
]}

Liu, Youjiang ^{[2
]}

Wang, Xiaozhi ^{[4
]}

Li, Shan ^{[2
]}

机构：

[1] Hefei Univ Technol, Sch Mech Engn, Hefei, Anhui, Peoples R China

[2] Hefei Inst Intelligent Machines, State Key Lab Transducer Technol, Hefei, Anhui, Peoples R China

[3] Dalhousie Univ, Dept Elect & Comp Engn, Halifax, NS, Canada

[4] Zhejiang Univ, Dept Informat Sci & Elect Engn, Hangzhou, Zhejiang, Peoples R China

来源：

EUROPEAN JOURNAL OF MASS SPECTROMETRY | 2018年 / 24卷 / 02期

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

High-field asymmetric waveform ion mobility spectrometry; intelligent detection method; peak scan; time saving; FAIMS;

D O I：

10.1177/1469066717743623

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

In conventional high-field asymmetric waveform ion mobility spectrometry signal acquisition, multi-cycle detection is time consuming and limits somewhat the technique's scope for rapid field detection. In this study, a novel intelligent detection approach has been developed in which a threshold was set on the relative error of alpha parameters, which can eliminate unnecessary time spent on detection. In this method, two full-spectrum scans were made in advance to obtain the estimated compensation voltage at different dispersion voltages, resulting in a narrowing down of the whole scan area to just the peak area(s) of interest. This intelligent detection method can reduce the detection time to 5-10% of that of the original full-spectrum scan in a single cycle.

引用

页码：191 / 195

页数：5

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