Metabolic programming: fetal origins of obesity and metabolic syndrome in the adult

被引：54

作者：

Ismail-Beigi, Faramarz ^{[1
]}

Catalano, Patrick M.

Hanson, Richard W.

机构：

[1] Case Western Reserve Univ, Sch Med, Dept Med, Cleveland Diabet Ctr, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Sch Med, Dept Reprod Biol, Cleveland Diabet Ctr, Cleveland, OH 44106 USA

[3] Case Western Reserve Univ, Sch Med, Dept Biochem, Cleveland Diabet Ctr, Cleveland, OH 44106 USA

来源：

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM | 2006年 / 291卷 / 03期

关键词：

D O I：

10.1152/ajpendo.00105.2006

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Exposure of the fetus to the intrauterine milieu can have profound effects on the health of the offspring in adulthood. Results of a series of studies demonstrate the powerful influence of the mother's metabolic state on whether the emerging adult develops obesity and hyperinsulinemia. Importantly, these attributes can be passed on to the next generation nongenetically and can be reversed and prevented.

引用

页码：E439 / E440

页数：2

共 50 条

[1] Maternal Obesity and the Fetal Origins of the Metabolic Syndrome
Rkhzay-Jaf, Jwan
O'Dowd, Jacqueline F.
Stocker, Claire J.
CURRENT CARDIOVASCULAR RISK REPORTS, 2012, 6 (05) : 487 - 495
[2] Maternal Obesity and the Fetal Origins of the Metabolic Syndrome
Jwan Rkhzay-Jaf
Jacqueline F. O’Dowd
Claire J. Stocker
Current Cardiovascular Risk Reports, 2012, 6 (5) : 487 - 495
[3] Fetal metabolic programming predisposes to adult-onset obesity
Patel, M
Srinivasan, M
Shbeir-ElDika, S
Aalinkeel, R
Song, F
Pliss, L
Mitrani, P
Pentney, R
Strutt, B
Hill, D
Damodaran, S
Devaskar, S
FASEB JOURNAL, 2005, 19 (04): : A259 - A259
[4] Fetal origins of the metabolic syndrome
Xita, Nektaria
Tsatsoulis, Agathocles
WOMEN'S HEALTH AND DISEASE, 2010, 1205 : 148 - 155
[5] Fetal Programming and Metabolic Syndrome
Rinaudo, Paolo
Wang, Erica
ANNUAL REVIEW OF PHYSIOLOGY, VOL 74, 2012, 74 : 107 - 130
[6] Fetal programming of the metabolic syndrome
Marciniak, Aleksandra
Patro-Malysza, Jolanta
Kimber-Trojnar, Zaneta
Marciniak, Beata
Oleszczuk, Jan
Leszczynska-Gorzelak, Boena
TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY, 2017, 56 (02): : 133 - 138
[7] A developmental perspective on the origins of obesity and metabolic syndrome
Choi, Yong-Sung
Hwang, Il-Tae
JOURNAL OF THE KOREAN MEDICAL ASSOCIATION, 2014, 57 (03): : 234 - 240
[8] Developmental origins of health and disease: experimental and human evidence of fetal programming for metabolic syndrome
de Gusmao Correia, M. L.
Volpato, A. M.
Aguila, M. B.
Mandarim-de-Lacerda, C. A.
JOURNAL OF HUMAN HYPERTENSION, 2012, 26 (07) : 405 - 419
[9] Developmental origins of health and disease: experimental and human evidence of fetal programming for metabolic syndrome
M L de Gusmão Correia
A M Volpato
M B Águila
C A Mandarim-de-Lacerda
Journal of Human Hypertension, 2012, 26 : 405 - 419
[10] Developmental origins of obesity and the metabolic syndrome: The role of maternal obesity
Armitage, James Andrew
Poston, Lucilla
Taylor, Paul David
OBESITY AND METABOLISM, 2008, 36 : 73 - 84

← 1 2 3 4 5 →