Synthesis of 5-[(1S)-endo]-bornyloxybutyrolactones bearing purine and pyrimidline bases

被引：0

作者：

Huang, H ^{[1
]}

Wang, ZD ^{[1
]}

Chen, QH ^{[1
]}

机构：

[1] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 19卷 / 06期

关键词：

purine and pyrimidine butyrolactones; physiological activity; asymmetric Michael addition; 5-[(1s)-endo]-bornyloxybutyrolactone epimers;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 5 - [(1S) - endo] - bomyloxybutyrolactones bearing purine and pyrimidine bases were obtained via the Michael addition of purines or pyrimidines to the epimeric mixture, 5 - [(IS) - endo] - bornyloxy - 2(5H) - furanones (3a + 3b),prepared from the natural abundant chiral auxiliary borneol and 5 - hydroxy - 2(5H) - furanone 2. The synthetic method was studied and the new compounds were identified on the basis of their analytical and spectroscopic,IR, UV, H-1 NMR, C-13 NMR,MS data.

引用

页码：630 / 635

页数：6