A retrospective study evaluating the clinical discernment of chin deviations in general, and especially in relation to unilateral posterior crossbite (UPXB), was carried out to determine whether (1) there is a correlation between UPXB and clinically discernible chin deviation, (2) there are differences between the judgement of professional dental observers and laymen, (3) visual assessment of chin deviation compares well with computer-assisted assessment and (4) how large a chin deviation should be before it is noticed. The experimental group consisted of 72 patients (30 males and 42 females, average age 14.5 years) with a UPXB. A control group of 72 subjects without a UPXB was matched for age and sex. In addition, one computer-designed face was added with chin deviations of 0, 2, 4, 6 and 8 mm to the left. The full-face slides of all subjects were shown twice, with an interval of 2 weeks, to an audience of seven orthodontists, ten dental students and five laymen judging by eye. A computer-assisted assessment was carried out by one observer, in order to create a standardized comparison to visual scoring. Inter-observer examination of visual scoring showed moderate agreement (kappa = 0.48). When comparing the computer-assisted and visual scores, the intra-class correlation coefficient (ICC) was 0.87. There were no major differences between professional observers and laymen, although the latter gave significantly more responses in the direction opposite to the crossbite. In 70.3 per cent (on average) of the subjects with a crossbite, a deviation in the same direction as the crossbite was noticed visually. The majority of the observers observed a chin deviation of at least 4 mm.