Interaction of stable colloidal nanoparticles with cellular membranes

被引：64

作者：

Mahmoudi, Morteza ^{[1
,2
]}

Meng, Jie ^{[3
]}

Xue, Xue ^{[3
]}

Liang, Xing Jie ^{[3
]}

Rahman, Masoud ^{[4
]}

Pfeiffer, Christian ^{[5
]}

Hartmann, Raimo ^{[5
]}

Gil, Pilar Rivera ^{[5
]}

Pelaz, Beatriz ^{[5
]}

Parak, Wolfgang J. ^{[5
,6
]}

del Pino, Pablo ^{[5
,6
]}

Carregal-Romero, Susana ^{[5
,7
]}

Kanaras, Antonios G. ^{[8
]}

Selvan, Subramanian Tamil ^{[9
,10
]}

机构：

[1] Univ Tehran Med Sci, Fac Pharm, Dept Nanotechnol, Tehran, Iran

[2] Univ Tehran Med Sci, Fac Pharm, Nanotechnol Res Ctr, Tehran, Iran

[3] Natl Ctr Nanosci & Technol China, Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China

[4] Univ Calif Davis, Dept Chem Engn & Mat Sci, Davis, CA 95616 USA

[5] Univ Marburg, Fachbereich Phys, D-35037 Marburg, Germany

[6] CIC biomaGUNE, San Sebastian 20009, Spain

[7] Andalusian Ctr Nanomed & Biotechnol BIONAND, Malaga 29590, Spain

[8] Univ Southampton, Fac Phys & Appl Sci, Inst Life Sci Phys & Astron, Southampton SO17 1BJ, Hants, England

[9] A STAR Inst Mat Res & Engn IMRE, Singapore 117602, Singapore

[10] Natl Univ Singapore, Div Bioengn, Fac Engn, Singapore 117576, Singapore

来源：

BIOTECHNOLOGY ADVANCES | 2014年 / 32卷 / 04期

关键词：

Nanoparticle; Colloid; Cell membrane; Receptor; Protein corona; Targeted delivery; MESOPOROUS SILICA NANOPARTICLES; IRON-OXIDE NANOPARTICLES; FUNCTIONALIZED GOLD NANOPARTICLES; POLYMER-COATED NANOPARTICLES; PHOTOTHERMAL THERAPY PPTT; SINGLE-PARTICLE TRACKING; OVERCOME DRUG-RESISTANCE; WALLED CARBON NANOTUBES; GENE DELIVERY SYNTHESIS; STATIC MAGNETIC-FIELD;

D O I：

10.1016/j.biotechadv.2013.11.012

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Due to their ultra-small size, inorganic nanoparticles (NPs) have distinct properties compared to the bulk form. The unique characteristics of NPs are broadly exploited in biomedical sciences in order to develop various methods of targeted drug delivery, novel biosensors and new therapeutic pathways. However, relatively little is known in the negotiation of NPs with complex biological environments. Cell membranes (CMs) in eukaryotes have dynamic structures, which is a key property for cellular responses to NPs. In this review, we discuss the current knowledge of various interactions between advanced types of NPs and CMs. (C) 2014 Elsevier Inc. All rights reserved.

引用

页码：679 / 692

页数：14

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