Host Mast Cells in Leishmaniasis: Friend or Foe?

被引：7
|
作者：
Naqvi, Nilofer [1 ,2 ]
Srivastava, Rahul [1 ]
Selvapandiyan, Angamuthu [3 ]
Puri, Niti [1 ]
机构：
[1] Jawaharlal Nehru Univ, Sch Life Sci, Cellular & Mol Immunol Lab, New Delhi 110067, India
[2] ICMR Natl Inst Pathol, Safdarjung Hosp Campus, New Delhi 110029, India
[3] Jamia Hamdard, Jamia Hamdard Inst Mol Med, New Delhi 110062, India
来源：
TRENDS IN PARASITOLOGY | 2020年 / 36卷 / 12期
关键词：
CUTANEOUS LEISHMANIASIS; SEVERITY; IMMUNE;
D O I：
10.1016/j.pt.2020.09.010
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Mast cells (MCs) are skin-resident immune cells whose role in leishmaniasis has been recently explored. Researchers report varying inferences, that is, mast cells promote, eliminate, or have no role in leishmaniasis. This article discusses this heterogeneity in mast cell roles to facilitate potential therapeutic and vaccine interventions for these diseases.
引用
收藏
页码：952 / 956
页数：5
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