Primary peripheral T-cell lymphoma, not otherwise specified, of the central nervous system in a child

被引：2

作者：

Momota, Hiroyuki ^{[1
]}

Kato, Seiichi ^{[2
,3
]}

Fujii, Masazumi ^{[1
]}

Tsujiuchi, Takashi ^{[1
]}

Takahashi, Yoshiyuki ^{[4
]}

Kojima, Seiji ^{[4
]}

Wakabayashi, Toshihiko ^{[1
]}

机构：

[1] Nagoya Univ Hosp, Dept Neurosurg, Showa Ku, Nagoya, Aichi 4668560, Japan

[2] Nagoya Univ Hosp, Dept Pathol, Nagoya, Aichi, Japan

[3] Nagoya Univ Hosp, Clin Labs, Nagoya, Aichi, Japan

[4] Nagoya Univ Hosp, Dept Pediat, Nagoya, Aichi, Japan

来源：

BRAIN TUMOR PATHOLOGY | 2015年 / 32卷 / 04期

基金：

日本学术振兴会;

关键词：

Peripheral T-cell lymphoma; Central nervous system; Radiochemotherapy; Pediatric; DIAGNOSIS;

D O I：

10.1007/s10014-015-0229-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Primary peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS), is a rare disease that infrequently involves the central nervous system (CNS), and it is even rarer in pediatric patients. Here, we report of a 13-year-old male with primary CNS PTCL-NOS who exhibited a malignant clinical course with recurrence after radiochemotherapy followed by bone marrow transplantation; he died 43 months after diagnosis. Pathology revealed the proliferation of cytotoxic T-cells and clonal T-cell receptor gene rearrangements. Although the optimal therapy for PTCL remains controversial, intensive radiochemotherapy may be required for some patients.

引用

页码：281 / 285

页数：5

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