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- [6] Lower Estradiol and Sex Hormone Binding Globulin Levels are Associated with higher Volumes of Ectopic Cardiovascular Fat in Women at Midlife: The Study of Women's Health Across the Nation (SWAN) Ectopic Cardiovascular Fat Ancillary Study MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2014, 21 (12): : 1326 - 1327