α-Amidobenzylation of Aryl and Alkenyl Halides via Palladium-catalyzed Suzuki-Miyaura Coupling with α-(Acylamino)benzylboronic Esters

被引：27
|
作者：
Ohmura, Toshimichi [1 ]
Awano, Tomotsugu [1 ]
Suginome, Michinori [1 ]
机构：
[1] Kyoto Univ, Dept Synthet Chem & Biol Chem, Grad Sch Engn, Nishikyo Ku, Kyoto 6158510, Japan
来源：
CHEMISTRY LETTERS | 2009年 / 38卷 / 07期
关键词：
ACID-DERIVATIVES; AMINOMETHYLATIONS; INHIBITION; ALDIMINES; CHLORIDES;
D O I：
10.1246/cl.2009.664
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The Suzuki-Miyaura coupling of alpha-(acetylatnino)benzyl-boronic esters with aryl and alkenyl halides has been achieved using a Pd/P(t-Bu)(3) catalyst with KF and H2O in 1,4-dioxane, giving a-substituted benzylamines in high yields.
引用
收藏
页码：664 / 665
页数：2
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