A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells

被引：108
|
作者：
Tan, Li [1 ]
Lin, Weiying [1 ]
Zhu, Sasa [1 ]
Yuan, Lin [1 ]
Zheng, Kaibo [1 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2014年 / 12卷 / 26期
关键词：
CAPILLARY ELECTROPHORETIC DETERMINATION; SELECTIVE DETECTION; SO2; SENSITIVITY; HYDRAZINE; SENSOR;
D O I：
10.1039/c4ob00132j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Based on a novel coumarin-quinolinium platform, probe 2 was rationally designed and synthesized as a novel ratiometric fluorescent sensor for sulfite anions. The probe exhibited a wide dynamic concentration range for sulfite anions in a PBS buffer (containing 1 mg mL(-1) BSA). More importantly, the probe was suitable for ratiometric fluorescence imaging in living cells with high sensitivity, favorable selectivity, and minimal cytotoxicity.
引用
收藏
页码：4637 / 4643
页数：7
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