New strategies for the repair of spinal cord injury

被引：4
|
作者：
Wu, Zhourui [1 ]
Zhao, Ziru [1 ]
Yu, Yan [1 ]
Hu, Xiao [1 ]
Xu, Wei [1 ]
Zeng, Zhili [1 ]
Sun, Yi Eve [2 ]
Cheng, Liming [1 ]
机构：
[1] Tongji Univ, Sch Med, Dept Spine Surg, Shanghai Tongji Hosp, Shanghai 200065, Peoples R China
[2] Tongji Univ, Sch Med, Translat Stem Cell Ctr, Shanghai Tongji Hosp, Shanghai 200065, Peoples R China
来源：
CHINESE SCIENCE BULLETIN | 2014年 / 59卷 / 31期
基金：
中国国家自然科学基金;
关键词：
Spinal cord injury; Secondary injury; Repair; Regeneration; Stem cells; OLFACTORY ENSHEATHING CELLS; NEURAL STEM-CELLS; TRAUMATIC BRAIN-INJURY; CENTRAL-NERVOUS-SYSTEM; FUNCTIONAL RECOVERY; SCHWANN-CELLS; AXON REGENERATION; EPITHELIAL-CELLS; HUMAN FETAL; RATS;
D O I：
10.1007/s11434-014-0484-2
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Spinal cord injury (SCI) leads to several neurologic damages to patients with sensory and motor function loss. Although some inspiring results were reported in animal, even in non-human primate models, the clinical translation of these research achievements barely move forward for the SCI patients. This review mainly focused on the pathogenesis of the primary and secondary injury, the clinical therapies and the new technologies in spinal cord injury. Moreover, the key scientific issues on this field were discussed in the review. Finally, some suggestions were proposed for the scientific and clinical researches.
引用
收藏
页码：4041 / 4049
页数：9
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