Results of PET dosimetry in the treatment of thyrotoxicosis by I-131

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作者
Pratt, BE
Flower, MA
McCready, VR
Harmer, CL
Ott, RJ
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R-3 [医学研究方法]; R3 [基础医学];
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摘要
Despite its long history, there are many different approaches to the treatment of thyrotoxicosis with radioiodine. Our aim in this study is to increase the probability of achieving a euthyroid state with a single administration of I-131. The parameters, uptake, effective half-life and volume, needed to calculate the activity of radioiodine for treatment and the subsequent radiation dose achieved, are determined from a I-124 tracer study and PET scanning. Preliminary results suggest that using this regime there is an increase in the number of patients becoming euthyroid after a single treatment as compared to those who received a fixed activity of radioiodine.
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页码:313 / 318
页数:6
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