Axonal regeneration inhibitors: emerging therapeutic options

被引：6

作者：

Rosochowicz, T. W. ^{[1
]}

Wrotek, S. ^{[1
]}

Kozak, W. ^{[1
]}

机构：

[1] Nicholas Copernicus Univ, Torun, Poland

来源：

ACTA NEUROLOGICA BELGICA | 2015年 / 115卷 / 04期

关键词：

Nogo-A; MAG; OMgp; Regeneration of the central nervous system; MYELIN-ASSOCIATED GLYCOPROTEIN; SPINAL-CORD; NEURITE OUTGROWTH; SIGNALING PATHWAY; RECEPTOR; RHO; CNS; IDENTIFICATION; PROTEIN; GROWTH;

D O I：

10.1007/s13760-015-0425-0

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

For the most part, the central nervous system is unable to regenerate. The majority of injuries of vascular, inflammatory, degenerative and traumatic aetiology lead to an irreversible loss of central nervous system function. The paper presents the role of Nogo-A, MAG and OMgp proteins in the inhibition of central nervous system regeneration, and their potential clinical significance.

引用

页码：527 / 532

页数：6

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