Brevetoxin B4 isolated from greenshell mussels Perna canaliculus, the major toxin involved in neurotoxic shellfish poisoning in New Zealand

被引:0
|
作者
Morohashi, A
Satake, M
Naoki, H
Kaspar, HF
Oshima, Y
Yasumoto, T
机构
[1] Tohoku Univ, Grad Sch Agr Sci, Dept Appl Bioorgan Chem, Aoba Ku, Sendai, Miyagi 9818555, Japan
[2] Suntory Inst Bioorgan Res, Osaka 618, Japan
[3] Cawthron Inst, Nelson, New Zealand
关键词
brevetoxin; neurotoxic shellfish poisoning; New Zealand; CID MS/MS;
D O I
10.1002/(SICI)1522-7189(199903/04)7:2<45::AID-NT34>3.0.CO;2-H
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
A new brevetoxin B analog, brevetoxin B4 (BTXB4), was isolated as the major toxin in greenshell mussels, Perna canaliculus, collected in New Zealand at the time of the neurotoxic shellfish poisoning incident. The new analog accounted for nearly two-thirds of the mouse lethality of the shellfish and was determined to be a mixture of N-myristoyl-BTXB2 and N-palmitoyl-BTXB2. Copyright (C) 1999 John Wiley & Sons, Ltd.
引用
收藏
页码:45 / 48
页数:4
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