Small sample Accelerator Mass Spectrometry for biomedical applications

被引：13
|
作者：
Salehpour, M. [1 ]
Hakansson, K. [1 ]
Possnert, G. [1 ]
机构：
[1] Dept Phys & Astron, Appl Nucl Phys Div, Ion Phys, SE-75120 Uppsala, Sweden
来源：
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS | 2015年 / 361卷
基金：
瑞典研究理事会;
关键词：
Accelerator Mass Spectrometry; Biomedical; Small sample size; Bomb-peak dating; DNA; INTRACAVITY OPTOGALVANIC SPECTROSCOPY; DYNAMICS; NEUROGENESIS; TURNOVER; AGE;
D O I：
10.1016/j.nimb.2015.04.047
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
The Accelerator Mass Spectrometry activities at Uppsala University include a group dedicated to the biomedical applications, involving natural level samples, as well as C-14-labeled substances requiring separate handling and preparation. For most applications sufficient sample amounts are available but many applications are limited to samples sizes in the mu g-range. We have developed a preparation procedure for small samples biomedical applications, where a few mu g C can be analyzed, albeit with compromised precision. The latest results for the small sample AMS method are shown and some of the biomedical activities at our laboratory are presented. (C) 2015 Elsevier B.V. All rights reserved.
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页码：43 / 47
页数：5
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