Convenient one-step synthesis of 5-carboxy-seminaphthofluoresceins

被引:1
|
作者
Hammershoj, Peter [1 ,2 ]
Thyrhaug, Erling [3 ]
Harris, Pernille [2 ]
Ek, Pramod K. [2 ,4 ]
Andresen, Thomas L. [2 ,4 ]
Clausen, Mads H. [1 ,2 ]
机构
[1] Tech Univ Denmark, Dept Chem, Bldg 207, DK-2800 Lyngby, Denmark
[2] Tech Univ Denmark, Ctr Nanomed & Theranost, DK-2800 Lyngby, Denmark
[3] Lund Univ, Dept Chem Phys, Getingevagen 60, S-22241 Lund, Sweden
[4] Tech Univ Denmark, DTU Nanotech, Dept Micro & Nanotechnol, DK-2800 Lyngby, Denmark
关键词
5-Carboxy-seminaphthofluoresceins; Near-infrared-emitter; One-step synthesis; Enhanced; Stokes shifts; DYES;
D O I
10.1016/j.tetlet.2017.03.028
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The one-step synthesis and characterization of a series of regioisomerically pure 5-carboxy-seminaphthofluoresceins (5-carboxy-SNAFLs) is reported. The optical properties were determined in aqueous buffer at around biological pH, and highly pH sensitive, large Stokes-shift fluorophores with emission in the deep-red to near-infrared region were identified. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1611 / 1615
页数:5
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