Interaction of 1-Propanol and 2-Propanol with Dipalmitoylphosphatidylcholine Bilayer: A Calorimetric Study

被引:14
|
作者
Wang, Yue [1 ]
Dea, Phoebe [1 ]
机构
[1] Occidental Coll, Dept Chem, Los Angeles, CA 90041 USA
来源
关键词
INTERDIGITATED GEL PHASE; CHAIN INTERDIGITATION; LIPID-BILAYERS; ETHANOL; BEHAVIOR; ALCOHOLS; DISTEAROYLPHOSPHATIDYLCHOLINE; PHOSPHATIDYLCHOLINES; TRANSITIONS; CHOLESTEROL;
D O I
10.1021/je800657m
中图分类号
O414.1 [热力学];
学科分类号
摘要
Differential scanning calorimetry (DSC) was employed to study the effects of 1-propanol and 2-propanol on the thermotropic behavior of dipalmitoylphosphatidylcholine (DPPC) bilayer membranes. The biphasic effect was observed in both systems based on an abrupt reversal in trend of the gel-to-liquid crystalline main transition temperatures upon heating. At this inflection point, a large hysteresis also occurred between the heating and cooling main transition temperatures, and the pretransition peaks disappeared. Such evidence indicated the formation of the interdigitated gel phase at this critical concentration, which was determined to be 0.39 mol.L-1 and 0.52 mol.L-1 for 1-propanol and 2-propanol, respectively. This threshold concentration was found to be higher for 2-propanol than for 1-propanol, suggesting that the shorter chain length and branching in 2-propanol caused it to be a less effective inducer for the interdigitated phase in DPPC. On some heating and cooling scans, an extra peak is observed around and beyond the critical concentration, indicating the presence of mixed phases as the interdigitated phase forms.
引用
收藏
页码:1447 / 1451
页数:5
相关论文
共 50 条
  • [1] Poisoning with 1-propanol and 2-propanol
    Vujasinovic, M.
    Kocar, M.
    Kramer, K.
    Bunc, M.
    Brvar, M.
    [J]. HUMAN & EXPERIMENTAL TOXICOLOGY, 2007, 26 (12) : 975 - 978
  • [2] Molecular Interaction of Aqueous Solution of 1-Propanol and 2-Propanol
    Sharma, Sandhya
    Kandpal, N. D.
    Joshi, R.
    [J]. ORIENTAL JOURNAL OF CHEMISTRY, 2019, 35 (02) : 901 - 904
  • [3] Etherification of isobutene with 1-propanol and 2-propanol
    Linnekoski, JA
    Krause, AOI
    Holmen, A
    Kjetsa, M
    Moljord, K
    [J]. APPLIED CATALYSIS A-GENERAL, 1998, 174 (1-2) : 1 - 11
  • [4] REACTIONS OF ATOMIC OXYGEN WITH 1-PROPANOL AND 2-PROPANOL
    AYUB, AL
    ROSCOE, JM
    [J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1979, 57 (11): : 1269 - 1273
  • [5] CALORIMETRIC STUDY OF THE INTERACTION OF LYSOZYME WITH AQUEOUS 1-PROPANOL
    STURTEVANT, JM
    VELICELEBI, G
    [J]. BIOCHEMISTRY, 1981, 20 (11) : 3091 - 3096
  • [6] PHYSICOCHEMICAL PROPERTIES OF ELECTROLYTES IN 1-PROPANOL AND 2-PROPANOL
    PIRUKHAL.NI
    MACHAIDZ.ZI
    [J]. ZHURNAL OBSHCHEI KHIMII, 1973, 43 (03): : 487 - 490
  • [7] Photodissociation dynamics of 1-propanol and 2-propanol at 193.3 nm
    Zhou, WD
    Yuan, Y
    Zhang, JS
    [J]. JOURNAL OF CHEMICAL PHYSICS, 2003, 119 (14): : 7179 - 7187
  • [8] Theoretical study of the reactions of triplet oxygen atom with 1-propanol and 2-propanol
    Shi, Gai
    Song, Jinou
    Tian, Pengzhen
    [J]. CHEMICAL PHYSICS LETTERS, 2021, 781
  • [9] Mixing properties of the liquid systems methanol plus 2-propanol and 1-propanol plus 2-propanol
    Haase, R
    Tillmann, W
    [J]. ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS, 1995, 192 : 121 - 131
  • [10] Electron solvation in 1-propanol and 2-propanol as a function of temperature
    Zhang, XJ
    Jonah, CD
    [J]. CHEMICAL PHYSICS LETTERS, 1996, 262 (05) : 649 - 655