Camel milk as an alternative treatment regimen for diabetes therapy

被引:27
|
作者
Hussain, Humaira [1 ]
Wattoo, Feroza Hamid [1 ]
Wattoo, Muhammad Hamid Sarwar [2 ]
Gulfraz, Muhammad [1 ]
Masud, Tariq [4 ]
Shah, Imam [3 ]
Ali, Sakhawat [3 ]
Alavi, Seyed Ebrahim [5 ]
机构
[1] PMAS Arid Agr Univ, Univ Inst Biochem & Biotechnol, Rawalpindi, Pakistan
[2] Pakistan Inst Engn & Appl Sci, Dept Chem, Islamabad, Pakistan
[3] Natl Vet Labs, Islamabad, Pakistan
[4] PMAS Arid Agr Univ, Dept Food Technol, Rawalpindi, Pakistan
[5] Pasteur Inst Iran, Dept Pilot Nanobiotechnol, Tehran, Iran
来源
FOOD SCIENCE & NUTRITION | 2021年 / 9卷 / 03期
关键词
antidiabetic activity; glibenclamide; hepatoprotective effect; triglyceride; OXIDATIVE STRESS; LIVER; EXTRACT; INJURY; ZINC; RATS;
D O I
10.1002/fsn3.2078
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Camel milk is a valuable source of nutrition with a wide range of therapeutic effects. Its unique composition helps to regulate the blood glucose level. The current study is aimed to evaluate the antidiabetic and hepatoprotective effects, as well as lipid profile restoration of camel milk in the diabetic mouse model. This innovative study evaluates the therapeutic effects of camel milk in diabetic mice by simultaneous measurement of blood glucose, HbA1c, ALT, AST, TG, cholesterol, and histopathological studies. The results showed that camel milk has significantly reduced blood glucose, HbA1c (p < .001), aspartate transaminase (AST), alanine transaminase (ALT) (p < .01), triglyceride (TG), and cholesterol (p < .01), compared to that in the diabetic control group. Also, the therapeutic effects of camel milk were completely comparable with the antidiabetic drug glibenclamide. The results of this study suggest that camel milk could be used as a proper alternative treatment regimen for diabetes therapy.
引用
收藏
页码:1347 / 1356
页数:10
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