Regulation of Wilms' tumor gene expression by nerve growth factor and follicle-stimulating hormone in the immature mouse ovary

被引:7
|
作者
Roh, Jaesook [1 ]
Bae, Jeehyeon [2 ]
Lee, Kangseok [3 ]
Mayo, Kelly [4 ]
Shea, Lonnie [5 ]
Woodruff, Teresa K. [4 ]
机构
[1] Hanyang Med Univ, Dept Obstet & Gynecol, Seoul, South Korea
[2] Pochon CHA Univ, Grad Sch Life Sci & Biotechnol, Seoul, South Korea
[3] Chung Ang Univ, Coll Nat Sci, Dept Life Sci, Seoul 156756, South Korea
[4] Northwestern Univ, Dept Biochem Mol Biol & Cell Biol, Evanston, IL USA
[5] Northwestern Univ, Dept Chem & Biol Engn, Evanston, IL USA
基金
美国国家卫生研究院;
关键词
INHIBIN-ALPHA GENE; MAMMALIAN OVARY; WT1; RECEPTOR; PROMOTER; CELLS;
D O I
10.1016/j.fertnstert.2008.07.012
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
This study investigated the regulation of Wilms' tumor gene (WT1) in the ovary by nerve growth factor and FSH to better understand signals that initiate early follicular growth. Nerve growth factor showed a direct stimulatory effect on endogenous expression of WT1, whereas FSH attenuated basal and nerve growth factor-stimulated WT1 protein expression, which most likely depended on FSH responsiveness according to the follicle growth stage. (Fertil Steril (R) 2009;91:1451-4. (C) 2009 by American Society for Reproductive Medicine.)
引用
收藏
页码:1451 / 1454
页数:4
相关论文
共 50 条
  • [1] The expression of nerve growth factor and follicle-stimulating hormone receptor in endometrial ovarian cysts
    Afshari-Stasiak, Susan
    Maria, Szubert
    Kobierzycki, Christopher
    Piotrowska, Aleksandra
    Rycerz, Aleksander
    Dziegiel, Piotr
    Sieroszewski, Piotr
    EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2024, 293 : 296 - 296
  • [2] Expression of follicle-stimulating hormone receptor in human ovary
    Minegishi, T
    Tano, M
    Igarashi, M
    Rokukawa, S
    Abe, Y
    Ibuki, Y
    Miyamoto, K
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1997, 27 (06) : 469 - 474
  • [3] Hormone-induced receptor gene splicing: Enhanced expression of the growth factor type I follicle-stimulating hormone receptor motif in the developing mouse ovary as a new paradigm in growth regulation
    Babu, PS
    Danilovich, N
    Sairam, MR
    ENDOCRINOLOGY, 2001, 142 (01) : 381 - 389
  • [4] Follicle-stimulating hormone promotes nerve growth factor and vascular endothelial growth factor expression in epithelial ovarian cells
    Garrido, Maritza P.
    Bruneau, Nicole
    Vega, Margarita
    Selman, Alberto
    Tapia, Julio C.
    Romero, Carmen
    HISTOLOGY AND HISTOPATHOLOGY, 2020, 35 (09) : 961 - 971
  • [5] Follicle-stimulating hormone/cAMP regulation of aromatase gene expression requires β-catenin
    Parakh, Tehnaz N.
    Hernandez, Jennifer A.
    Grammer, Jean C.
    Weck, Jennifer
    Hunzicker-Dunn, Mary
    Zeleznik, Anthony J.
    Nilson, John H.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (33) : 12435 - 12440
  • [6] Lysyl oxidase gene expression and enzyme activity in the rat ovary:: Regulation by follicle-stimulating hormone, androgen, and transforming growth factor-β superfamily members in vitro
    Harlow, CR
    Rae, M
    Davidson, L
    Trackman, PC
    Hillier, SG
    ENDOCRINOLOGY, 2003, 144 (01) : 154 - 162
  • [7] Developmental regulation of follicle-stimulating hormone receptor messenger RNA expression in the baboon fetal ovary
    Zachos, NC
    Billiar, RB
    Albrecht, ED
    Pepe, GJ
    BIOLOGY OF REPRODUCTION, 2003, 68 (05) : 1911 - 1917
  • [8] Developmental expression of estrogen receptor (ER) α and ERβ in the hamster ovary:: Regulation by follicle-stimulating hormone
    Yang, PX
    Wang, JR
    Shen, YL
    Roy, SK
    ENDOCRINOLOGY, 2004, 145 (12) : 5757 - 5766
  • [9] Progesterone and regulation of the follicle-stimulating hormone (FSH-β) gene
    O'Conner, JL
    Wade, MF
    Edwards, DP
    Mahesh, VB
    STEROIDS, 1999, 64 (09) : 592 - 597
  • [10] Current Concepts of Follicle-Stimulating Hormone Receptor Gene Regulation
    George, Juin W.
    Dille, Elizabeth A.
    Heckert, Leslie L.
    BIOLOGY OF REPRODUCTION, 2011, 84 (01) : 7 - 17