GTS-21, a selective α7 nicotinic acetylcholine receptor agonist, ameliorates septic ileus in a mouse cecal ligation and puncture model

被引:0
|
作者
Nullens, S. [1 ]
De Man, J. G. [1 ]
Pelckmans, P. A. [1 ,2 ]
De Winter, B. Y. [1 ]
机构
[1] Univ Antwerp, Div Gastroenterol & Hepatol, Lab Expt Med & Pediat, Antwerp, Belgium
[2] Univ Antwerp Hosp, Dept Gastroenterol & Hepatol, Antwerp, Belgium
来源
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
PP042
引用
收藏
页码:23 / 23
页数:1
相关论文
共 50 条
  • [1] GTS-21, a Selective Alpha7 Nicotinic Acetylcholine Receptor Agonist, Ameliorates Impaired Mucosal Barrier Function and Inhibits Bacterial Translocation in a Mouse Cecal Ligation and Puncture Model
    Nullens, Sara
    Staessens, Michael
    Peleman, Cedric
    Pelckmans, Paul A.
    Lammens, Christine
    Malhotra-Kumar, Surbhi
    De Man, Joris G.
    De Winter, Benedicte Y.
    [J]. GASTROENTEROLOGY, 2015, 148 (04) : S141 - S142
  • [2] Effects of splenectomy and GTS-21, a selective α7 nicotinic acetylcholine receptor agonist, on the development of septic ileus in mice
    S Nullens
    JG De Man
    PA Pelckmans
    BY De Winter
    [J]. Critical Care, 18 (Suppl 2):
  • [3] GTS-21, a selective alpha7 nicotinic acetylcholine receptor agonist, ameliorates diabetic nephropathy in Leprdb/db mice
    Meng, Qinghe
    Tian, Xinghan
    Li, Junwei
    Pruekprasert, Napat
    Dhawan, Ravi
    Holz, George G.
    Cooney, Robert N.
    [J]. SCIENTIFIC REPORTS, 2022, 12 (01)
  • [4] GTS-21, a selective alpha7 nicotinic acetylcholine receptor agonist, ameliorates diabetic nephropathy in Leprdb/db mice
    Qinghe Meng
    Xinghan Tian
    Junwei Li
    Napat Pruekprasert
    Ravi Dhawan
    George G. Holz
    Robert N. Cooney
    [J]. Scientific Reports, 12
  • [5] ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONIST (GTS-21) ATTENUATES INTESTINAL INJURY IN SEPSIS
    Xie, Han
    Meng, Qinghe
    Pruekprasert, Napat
    Liu, Yu
    Cooney, Robert
    [J]. SHOCK, 2020, 53 : 67 - 67
  • [6] EFFECTS OF THE α7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONIST GTS-21 ON THE INNATE IMMUNE RESPONSE IN HUMANS
    Kox, Matthijs
    Pompe, Jan C.
    de Gouberville, Marije C. Gordinou
    van der Hoeven, Johannes G.
    Hoedemaekers, Cornelia W.
    Pickkers, Peter
    [J]. SHOCK, 2011, 36 (01): : 5 - 11
  • [7] The selective α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced inflammation and lung injury
    M Kox
    JC Pompe
    M Vaneker
    LM Heunks
    JG Van der Hoeven
    CW Hoedemaekers
    P Pickkers
    [J]. Critical Care, 13 (Suppl 1):
  • [8] Selective α7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis
    Pavlov, Valentin A.
    Ochani, Mahendar
    Yang, Li-Hong
    Gallowitsch-Puerta, Margot
    Ochani, Kanta
    Lin, Xinchun
    Levi, Jelena
    Parrish, William R.
    Rosas-Ballina, Mauricio
    Czura, Christopher J.
    LaRosa, Gregory J.
    Miller, Edmund J.
    Tracey, Kevin J.
    Al-Abed, Yousef
    [J]. CRITICAL CARE MEDICINE, 2007, 35 (04) : 1139 - 1144
  • [9] Reduction of aggressive behavior in mouse models by the selective α7 nicotinic partial agonist GTS-21
    Lewis, Alan S.
    Garvey, Katherine
    Mineur, Yann S.
    Picciotto, Marina R.
    [J]. BIOCHEMICAL PHARMACOLOGY, 2015, 97 (04) : 632 - 633
  • [10] Alpha-7 nicotinic acetylcholine receptor agonist GTS-21 influences the inflammatory response in an animal model of heart failure
    Kha, Mindy
    Chow, Sheryl
    Cameron, D. Joshua
    O'Barr, Stephen A.
    [J]. JOURNAL OF IMMUNOLOGY, 2017, 198 (01):