The Genomic Landscape of Anal Cancer and Its Relationship to Clinical Outcomes: An Exploratory Analysis of NRG Oncology/RTOG 98-11

被引：0
|
作者：
Konieczkowski, D. J. [1 ,2 ]
Rawal, B. [3 ]
Reardon, B. [2 ,4 ]
Park, J. [2 ,4 ]
Ajidahun, A. [5 ]
Mamon, H. J. [6 ,7 ]
Shibata, D. [5 ]
Ajani, J. [8 ]
Benson, A. [9 ]
Thomas, C. R., Jr. [10 ]
Haddock, M. G. [11 ]
Okawara, G. S. [12 ]
Pizzolato, J. [13 ]
Catalano, P. S. [3 ]
Moughan, J. [14 ]
Dicker, A. P. [15 ]
Van Allen, E. M. [2 ,4 ]
Mouw, K. W. [2 ,16 ,17 ]
机构：
[1] Harvard Radiat Oncol Program, Boston, MA USA
[2] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA
[3] Harvard Med Sch, Dana Farber Canc Inst, Dept Biostat & Computat Biol, Boston, MA 02115 USA
[4] Harvard Med Sch, Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA
[5] Univ Tennessee, Ctr Hlth Sci, Dept Surg, Memphis, TN 38163 USA
[6] Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA
[7] Dana Farber Canc Inst, Boston, MA 02115 USA
[8] Univ Texas MD Anderson Canc Ctr, Dept Gastrointestinal Med Oncol, Houston, TX 77030 USA
[9] Northwestern Univ, Div Hematol & Oncol, Chicago, IL 60611 USA
[10] Oregon Hlth & Sci Univ, Dept Radiat Oncol, Portland, OR 97201 USA
[11] Mayo Clin, Dept Radiat Oncol, Rochester, MN USA
[12] Juravinski Canc Ctr, Div Radiat Oncol, Hamilton, ON, Canada
[13] Mt Sinai Med Ctr, Dept Hematol Oncol, Miami Beach, FL 33140 USA
[14] NRG Oncol Stat & Data Management Ctr ACR, Philadelphia, PA USA
[15] Thomas Jefferson Univ, Sidney Kimmel Med Coll & Canc Ctr, Dept Radiat Oncol, Philadelphia, PA 19107 USA
[16] Dana Farber Canc Inst, Dept Radiat Oncol, Boston, MA 02115 USA
[17] Harvard Med Sch, Brigham & Womens Hosp, Boston, MA 02115 USA
来源：
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2019年 / 105卷 / 01期
关键词：
D O I：
10.1016/j.ijrobp.2019.06.594
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
215
引用
收藏
页码：S104 / S105
页数：2
相关论文
共 33 条
  • [1] Methylomic Classifiers of Anal Cancer Outcomes: An NRG Oncology/RTOG 98-11 Tissue Study
    Siegel, E.
    Eschrich, S. A.
    Berglund, A. E.
    Ajidahun, A.
    Magliocco, A. M.
    Putney, R.
    Riggs, B.
    Moughan, J.
    Hoffe, S.
    Simko, J. P.
    Ajani, J.
    Guha, C.
    Okawara, G.
    Clouse, J. W.
    Becker, M. J.
    Pizzolato, J. F.
    Crane, C. H.
    Shibata, D.
    ANNALS OF SURGICAL ONCOLOGY, 2017, 24 : S23 - S24
  • [2] Methylomic classifiers of anal cancer outcomes: An NRG Oncology / RTOG 98-11 tissue study.
    Siegel, Erin M.
    Eschrich, Steven A.
    Berglund, Anders E.
    Ajidahun, Abidemi O.
    Magliocco, Anthony Martin
    Putney, Ryan
    Riggs, Bridget
    Moughan, Jennifer
    Hoffe, Sarah E.
    Simko, Jeff
    Ajani, Jaffer A.
    Guha, Chandan
    Okawara, Gordon S.
    Clouse, John W.
    Becker, Mark J.
    Pizzolato, Joseph F.
    Crane, Christopher H.
    Shibata, David
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (04)
  • [3] COMPREHENSIVE HUMAN PAPILLOMAVIRUS GENOTYPING AND OUTCOMES IN ANAL CANCER: AN NRG ONCOLOGY/RTOG 98-11 TISSUE SPECIMEN STUDY.
    Siegel, E.
    Moughan, J.
    Ajidahun, A.
    Magliocco, A.
    Riggs, B.
    Simko, J.
    Guha, C.
    Shibata, D.
    DISEASES OF THE COLON & RECTUM, 2016, 59 (05) : E113 - E114
  • [4] Epigenomic profiling of anal cancer: does size matter? An RTOG 98-11 specimen study
    Siegel, Erin
    Eschrich, Steven
    Winter, Kathryn
    Riggs, Bridget
    Berglund, Anders
    Ajidahun, Abidemi
    Simko, Jeff
    Ajani, Jaffer
    Magliocco, Anthony
    Elahi, Abul
    Coppola, Domenico
    Shibata, David
    SEXUAL HEALTH, 2013, 10 (06) : 590 - 590
  • [5] EPIGENOMIC CHARACTERIZATION OF LOCALLY ADVANCED STAGE ANAL CANCER: AN RTOG 98-11 SPECIMEN STUDY
    Siegel, E.
    Eschrich, S.
    Winter, K.
    Riggs, B.
    Ajidahun, A.
    Berglund, A.
    Simko, J.
    Ajani, J.
    Magliocco, A.
    Elahi, A.
    Coppola, D.
    Shibata, D.
    DISEASES OF THE COLON & RECTUM, 2013, 56 (04) : E90 - E90
  • [6] Prognostic Factors Derived from A Prospective Database Dictate Clinical Biology of Anal Cancer The Intergroup Trial (RTOG 98-11)
    Ajani, Jaffer A.
    Winter, Kathryn A.
    Gunderson, Leonard L.
    Pedersen, John
    Benson, Al B., III
    Thomas, Charles R., Jr.
    Mayer, Robert J.
    Haddock, Michael G.
    Rich, Tyvin A.
    Willett, Christopher G.
    CANCER, 2010, 116 (17) : 4007 - 4013
  • [7] Reduced Retinoblastoma (Rb) Protein is Associated with Improved Survival in Anal Cancer: RTOG 98-11 Specimen Study
    Siegel, Erin
    Moughan, Jennifer
    Magliocco, Anthony M.
    Winter, Kathryn
    Simko, Jeff
    Ajani, Jaffer
    Klimowicz, Alexander
    Doll, Corinne
    Guha, Chandan
    Shibata, David
    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2014, 219 (03) : S22 - S22
  • [8] The Significance of p16 and p53 Expression on Clinical Outcome in Patients with Anal Cancer Treated with Chemoradiation Therapy: An Analysis of RTOG 98-11
    Doll, C. M.
    Winter, K.
    Ajani, J.
    Klimowicz, A.
    Crane, C.
    Kachnic, L.
    Okawara, G.
    Lukka, H.
    Berk, L.
    Roof, K.
    Becker, M.
    Grisell, D.
    Guha, C.
    Magliocco, A. M.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2014, 90 : S32 - S32
  • [9] Epigenomic Characterization of Locally Advanced Anal Cancer: A Radiation Therapy Oncology Group 98-11 Specimen Study
    Siegel, Erin M.
    Eschrich, Steven
    Winter, Kathryn
    Riggs, Bridget
    Berglund, Anders
    Ajidahun, Abidemi
    Simko, Jeff
    Moughan, Jennifer
    Ajani, Jaffer
    Magliocco, Anthony
    Elahi, Abul
    Hoffe, Sarah
    Shibata, David
    DISEASES OF THE COLON & RECTUM, 2014, 57 (08) : 941 - 957
  • [10] The Significance of Coexpression of Epidermal Growth Factor Receptor (EGFR) and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiation Therapy: An Analysis of RTOG 98-11
    Doll, C.
    Moughan, J.
    Klimowicz, A. C.
    Lees-Miller, S. P.
    Ajani, J. A.
    Crane, C. H.
    Kachnic, L. A.
    Okawara, G.
    Guha, C.
    Magliocco, A. M.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2012, 84 (03): : S145 - S145
1234