Reusable silica supported poly phosphoric acid catalyzed three-component synthesis of 2H-indazolo[2,1-b]phthalazine-trione derivatives

被引:107
|
作者
Shaterian, Hamid Reza [1 ]
Hosseinian, Asghar [1 ]
Ghashang, Majid [1 ]
机构
[1] Univ Sistan & Baluchestan, Fac Sci, Dept Chem, POB 98135-674, Zahedan, Iran
关键词
PPA-SiO2; indazolo[2,1-b]phthalazine-trione; multi-component reaction; phthalhydrazide; dimedone; ONE-POT PREPARATION; HETEROGENEOUS CATALYST; EFFICIENT; HCLO4-SIO2; HYDROGENSULFATE; CONDENSATION;
D O I
10.3998/ark.5550190.0010.207
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient synthesis of 2H-indazolo[2,1-b]phthalazine-1,6,11(13H)-trione derivatives from the three-component condensation reaction of phthalhydrazide, dimedone, and aromatic aldehydes under solvent-free conditions in good to excellent yields and short reaction times using reusable silica supported poly phosphoric acid (PPA-SiO2) as heterogeneous acid catalyst has been investigated.
引用
收藏
页码:59 / 67
页数:9
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