DEXTENZA™ (extended release dexamethasone) 0.4 mg vs. Placebo for the Treatment of Ocular Pain after Cataract Surgery: Results of Three Phase 3 Studies

被引：0

作者：

Sane, Swati ^{[1
]}

Bafna, Shamik ^{[2
]}

Berdahl, John P. ^{[3
]}

Endl, Michael ^{[4
]}

Gira, Joseph P. ^{[5
]}

Protzko, Eugene ^{[6
]}

Singh, Inder Paul ^{[7
]}

Tyson, Sydney L. ^{[8
]}

Walters, Thomas R. ^{[9
]}

Wortz, Gary ^{[10
]}

Metzinger, Jamie Lynne ^{[1
]}

Mulani, Deepa ^{[1
]}

Talamo, Jonathan H. ^{[1
]}

机构：

[1] Ocular Therapeutix, Bedford, MA USA

[2] Cleveland Eye Clin, Elyria, OH USA

[3] Vance Thompson Vis, Sioux Falls, SD USA

[4] Fichte Endl & Elmer Eyecare, Amherst, NY USA

[5] Ophthalmol Consultants, St Louis, MO USA

[6] Seidenberg Protzko Eye Associates, Havre De Grace, MA USA

[7] Eye Ctr Racine & Kenosha, Racine, WI USA

[8] SurgiCtr Vineland, Vineland, NJ USA

[9] Keystone Res Ltd, Austin, TX USA

[10] Koffler Vis Grp, Lexington, KY USA

来源：

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2017年 / 58卷 / 08期

关键词：

D O I：

暂无

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

1826

引用

页数：4

共 10 条

[1] Results of a Phase 3, Randomized, Double-Masked, Vehicle Controlled Study (Phase 3c) Evaluating the Safety and Efficacy of DEXTENZA™ (dexamethasone insert) 0.4 mg for the Treatment of Ocular Inflammation and Pain after Cataract Surgery
Talamo, Jonathan H.
Tyson, Sydney L.
Bafna, Shamik
Joseph, Gira P.
Goldberg, Damien F.
Jones, Jason J.
Jones, Michael P.
Kim, Janet K.
Martel, James B.
Nordlund, Michael L.
Piovanetti, Ian K.
Singh, Inder Paul
Metzinger, Jamie Lynne
Mulani, Deepa
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2017, 58 (08)
[2] Sustained-release dexamethasone for the treatment of ocular inflammation and pain after cataract surgery
Walters, Thomas
Endl, Michael
Elmer, Thomas R.
Levenson, Jeffrey
Majmudar, Parag
Masket, Samuel
JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 2015, 41 (10): : 2049 - 2059
[3] Multicenter randomized phase 3 study of a sustained-release intracanalicular dexamethasone insert for treatment of ocular inflammation and pain after cataract surgery
Tyson, Syd L.
Bafna, Shamik
Gira, Joseph P.
Goldberg, Damien F.
Jones, Jason J.
Jones, Michael P.
Kim, Janet K.
Martel, Joseph M.
Nordlund, Michael L.
Piovanetti-Perez, Ian K.
Singh, Inder Paul
Metzinger, Jamie Lynne
Mulani, Deepa
Sane, Swati
Talamo, Jonathan H.
Goldstein, Michael H.
Alpem, Louis
Chu, Y. Ralph
Desai, Neel
Epitropoulos, Alice
Kozlovsky, John F.
Lesher, Mark
Malhotra, Ranjan P.
Peters, Newton T.
Price, Francis W., Jr.
Qamar, Tariq
Silverstein, Steven M.
Tekwani, Navin H.
Vroman, David T.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 2019, 45 (02): : 204 - 212
[4] Sustained-release dexamethasone for the treatment of ocular inflammation and pain after cataract surgery (vol 41, pg 2049, 2015)
不详
JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 2016, 42 (03): : 512 - 512
[5] Multicenter randomized phase 3 study of a sustained-release intracanalicular dexamethasone insert for treatment of ocular inflammation and pain after cataract surgery (vol 45, pg 204, 2019)
Tyson, S. L.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 2019, 45 (06): : 895 - 895
[6] Intracameral phenylephrine and ketorolac during cataract surgery to maintain intraoperative mydriasis and reduce postoperative ocular pain: Integrated results from 2 pivotal phase 3 studies
Hovanesian, John A.
Sheppard, John D.
Trattler, William B.
Gayton, Johnny L.
Malhotra, Ranjan P.
Schaaf, David T.
Ng, Edmund
Dunn, Steven H.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 2015, 41 (10): : 2060 - 2068
[7] Effects of Intravenous Solanezumab 400 mg q 4 Weeks vs. Placebo on Biomarkers in Patients with Mild to Moderate Alzheimer's Disease: Results of Two Phase 3 Studies
Hake, Ann
Siemers, Eric
Carlson, Christopher
Estergard, Wahiba
Sundell, Karen
Henley, David
Eads, Jennifer
Sexton, Cora
Liu-Seifert, Hong
Sethuraman, Gopalan
Chen, Yun-Fei
Mintun, Mark
Pontecorvo, Michael
Joshi, Abhinay
Dean, Robert
Willis, Brian
Demattos, Ronald
Mohs, Richard
NEUROLOGY, 2013, 80
[8] Intracameral phenylephrine and ketorolac during cataract surgery to maintain intraoperative mydriasis and reduce postoperative ocular pain: Integrated results from 2 pivotal phase 3 studies (vol 41, pg 2060, 2015)
Hovanesian, J. A.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 2016, 42 (02): : 349 - 349
[9] Intracameral phenylephrine and ketorolac during cataract surgery to maintain intraoperative mydriasis and reduce postoperative ocular pain: Integrated results from 2 pivotal phase 3 studies (vol 41, pg 2060, 2015)
Hovanesian, J. A.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 2016, 42 (06): : 951 - 951
[10] Serplulimab vs. placebo combined with chemotherapy as first-line treatment for extensive-stage small-cell lung cancer: Extended follow-up results and patient-reported outcomes from the international phase 3 ASTRUM-005 study.
Cheng, Ying
Han, Liang
Wu, Lin
Chen, Jun
Sun, Hongmei
Wen, Guilan
Ji, Yinghua
Zimina, Anastasia V.
Shi, Jianhua
Pan, Zhijie
Shi, Jinsheng
Wang, Xicheng
Bai, Yuansong
Melkadze, Tamar
Pan, Yueyin
Min, Xuhong
Viguro, Maksym
Li, Jing
Wang, Qingyu
Zhu, Jun
JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)

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