CLIP-170 family members: A motor-driven ride to microtubule plus ends

被引:11
|
作者
Maekawa, H [1 ]
Schiebel, E [1 ]
机构
[1] Paterson Inst Canc Res, Manchester M20 4BX, Lancs, England
关键词
D O I
10.1016/j.devcel.2004.05.017
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
CLIP-170 family proteins regulate microtubule plus end dynamics. Two reports published in this issue of Developmental Cell show that Bik1 and tip1p, the CLIP-170-like proteins of budding and fission yeast, are carried to microtubule plus ends by kinesin motor proteins. These findings indicate a complex interplay between microtubule-associated proteins and suggest a novel mechanism by which kinesin proteins stabilize microtubules.
引用
收藏
页码:746 / 748
页数:3
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