RESCUE OF HEMATOPOIETIC FAILURE INDUCED BY THE GATA 1(LOW) MUTATION IS MEDIATED BY A PERMISSIVE MICROENVIRONMENT IN THE SPLEEN THAT INDUCES DIFFERENTIATION OF GATA-1(LOW) PROGENITORS THROUGH THE ALTERNATIVE ENHANCER HS2

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作者
Migliaccio, A. R. [1 ]
Martelli, F. [2 ]
Verrucci, M. [2 ]
Fabucci, M. E. [2 ]
Sanchez, M. [2 ]
Migliaccio, G. [2 ]
Vannucchi, A. M. [3 ]
Zingariello, M. [4 ]
Di Baldassarre, A. [4 ]
Ghinassi, B. [4 ]
Rana, R. A. [4 ]
Van Hensbergen, Y. [5 ]
Fibbe, W. [5 ]
机构
[1] Mt Sinai Sch Med & Myeloproliferat Dis Reser, New York, NY USA
[2] Ist Super Sanita, I-00161 Rome, Italy
[3] Univ Florence, Florence, Italy
[4] Univ G dAnnunzio, Chieti, Italy
[5] Leiden Univ, Med Ctr, Leiden, Netherlands
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R5 [内科学];
学科分类号
1002 ; 100201 ;
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页码:1 / 1
页数:1
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  • [1] Gata1 expression driven by the alternative HS2 enhancer in the spleen rescues the hematopoietic failure induced by the hypomorphic Gata1low mutation
    Migliaccio, Anna Rita
    Martelli, Fabrizio
    Verrucci, Maria
    Sanchez, Massimo
    Valeri, Mauro
    Migliaccio, Giovanni
    Vannucchi, Alessandro Maria
    Zingariello, Maria
    Di Baldassarre, Angela
    Ghinassi, Barbara
    Rana, Rosa Alba
    van Hensbergen, Yvette
    Fibbe, Willem E.
    BLOOD, 2009, 114 (10) : 2107 - 2120