Dietary Exposure to Acrylamide and Associated Health Risks for the Korean Population

被引:18
|
作者
Lee, Sanghee [1 ]
Kim, Hyun Jung [2 ,3 ]
机构
[1] Korea Food Res Inst, Res Grp Nat Mat & Metab, Jeollabuk Do 55365, South Korea
[2] Korea Food Res Inst, Res Grp Consumer Safety, Jeollabuk Do 55365, South Korea
[3] Univ Sci & Technol, Dept Food Biotechnol, Daejeon 34113, South Korea
关键词
acrylamide; food products; dietary exposure; risk assessment; margin of exposure; LC-MS/MS; CHROMATOGRAPHY; MITIGATION; TOXICITY; FOODS;
D O I
10.3390/ijerph17207619
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The aim of the study was to estimate the dietary exposure to acrylamide (AA) from the consumption of various processed food and to assess the associated health risks in different age groups in Korea. Potato crisps and French fries presented the highest mean levels of AA (546 and 372 mu g/kg, respectively) followed by coffee (353 mu g/kg) and tea products (245 mu g/kg). The mean AA dietary exposure values for toddlers (<= 2 years), children (3-6 years), children (7-12 years), adolescents (13-19 years), adults (20-64 years), and seniors (>= 65 years) were estimated to be 0.15, 0.13, 0.06, 0.06, 0.08, and 0.06 mu g/kg body weight (BW)/day, respectively. Based on the benchmark dose lower confidence limit (BMDL10) of 0.18 and 0.31 mg/kg BW/day, the calculated mean and 95th percentile values for the margin of exposure were below 10,000 for the all age groups suggesting possible health concern for Koreans. Biscuits, crisps, and coffee were the primary foods contributing to dietary AA exposure among these in the Korean populations. In children, considering the health risk of AA dietary exposure, especially from biscuits and crisps, there is a need to further control and modify dietary habits to ensure lower AA exposure.
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页码:1 / 11
页数:11
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