DESIGN AND FABRICATION OF A ROLLER IMPRINTING DEVICE FOR MICROFLUIDIC DEVICE MANUFACTURING

被引:0
|
作者
Vijayaraghavan, Athulan [1 ]
Jayanathan, Stephen V. [1 ]
Helu, Moneer M. [1 ]
Dornfeld, David A. [1 ]
机构
[1] Univ Calif Berkeley, Dept Mech Engn, Lab Mfg & Sustainabil, Berkeley, CA 94720 USA
关键词
POLY(DIMETHYLSILOXANE); SYSTEMS;
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Microfluidic devices are gaining popularity in a variety of applications, ranging from molecular biology to bio-defense. However, the widespread adoption of this technology is constrained by the lack of efficient and cost-effective manufacturing processes. This paper focuses on the roller imprinting process, which is being developed to rapidly and inexpensively fabricate micro-fluidic devices. In this process, a cylindrical roll with raised features on its surface creates imprints by rolling over a fixed workpiece substrate and mechanically deforming it. Roller imprinting aims to replace processes that were developed for laboratory scale prototyping which tend to not be scalable and have high equipment requirements and overheads. We discuss the limitations of PDMS soft lithography in large-scale manufacture of microfluidic devices. We also discuss the design, fabrication, and testing of a simple roller imprinting device. This imprinter has been developed based on the principles of precision machine design and is implemented using a three-axis machine too] for actuation and position measurement. A framework for the micromachining of precision imprint rolls is also presented.
引用
收藏
页码:551 / 560
页数:10
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